GR 46611
TL;DR: GR 46611 (CAS 185259-85-2) is a chemical compound with molecular formula C23H27N3O2 and molecular weight 377.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]prop-2-enamide
Also Known As: GR 46611, GR46611;GR 46611, 3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]-2-propenamide, 3-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-(4-methoxybenzyl)acrylamide, 3-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]prop-2-enamide
| Molecular Formula | C23H27N3O2 |
|---|---|
| Molecular Weight | 377.21 g/mol |
| LogP | 3.2 |
| Topological Polar Surface Area | 57.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 8 |
| Exact Mass | 377.21033 |
| Heavy Atoms | 28 |
| Complexity | 514.0 |
Chemical Identifiers
| CAS Number | 185259-85-2 |
|---|---|
| SMILES | CN(C)CCC1=CNC2=C1C=C(C=C2)C=CC(=O)NCC3=CC=C(C=C3)OC |
| InChIKey | LBVZWEWTNUDWNS-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
GR 46611 (CAS 185259-85-2), with molecular formula C23H27N3O2 and molecular weight 377.21 g/mol. IUPAC: 3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]prop-2-enamide.
Chemical Property Profile of GR 46611
Property Insights of GR 46611
The XLogP value of 3.2 indicates that GR 46611 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.4 Ų, GR 46611 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, GR 46611 has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of GR 46611?
The CAS number of GR 46611 is 185259-85-2.
What is the molecular formula of GR 46611?
The molecular formula of GR 46611 is C23H27N3O2.
What is the molecular weight of GR 46611?
The molecular weight of GR 46611 is 377.21 g/mol.
Where can I buy GR 46611?
You can request a quote for GR 46611 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for GR 46611?
Yes, KEHONG BIO provides custom synthesis services for GR 46611 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.