![2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42 structure](/static/products/1850/185039-67-2.webp)
2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42
TL;DR: 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42 (CAS 185039-67-2) is a chemical compound with molecular formula C19H13Cl2N5O and molecular weight 397.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(2,6-dichlorophenyl)-8-methyl-2-(pyridin-4-ylamino)pyrido[2,3-d]pyrimidin-7-one
Also Known As: PD 166285 analog, 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42, 6-(2,6-Dichlorophenyl)-8-methyl-2-(4-pyridinylamino)-pyrido[2,3-d]pyrimidin-7(8h)-one, 6-(2,6-dichlorophenyl)-8-methyl-2-(4-pyridinylamino)pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2,6-dichlorophenyl)-8-methyl-2-(pyridin-4-ylamino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one
| Molecular Formula | C19H13Cl2N5O |
|---|---|
| Molecular Weight | 397.05 g/mol |
| LogP | 4.4409 |
| Topological Polar Surface Area | 72.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 397.0497 |
| Heavy Atoms | 27 |
| Complexity | 1187.8518 |
Chemical Identifiers
| CAS Number | 185039-67-2 |
|---|---|
| SMILES | CN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=CC=C3Cl)Cl)NC4=CC=NC=C4 |
Product Overview
2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42 (CAS 185039-67-2), with molecular formula C19H13Cl2N5O and molecular weight 397.05 g/mol. IUPAC: 6-(2,6-dichlorophenyl)-8-methyl-2-(pyridin-4-ylamino)pyrido[2,3-d]pyrimidin-7-one.
Chemical Property Profile of 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42
Property Insights of 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42
The XLogP value of 4.4409 indicates that 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42. Following Lipinski's Rule of Five, 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42?
The CAS number of 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42 is 185039-67-2.
What is the molecular formula of 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42?
The molecular formula of 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42 is C19H13Cl2N5O.
What is the molecular weight of 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42?
The molecular weight of 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42 is 397.05 g/mol.
Where can I buy 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42?
You can request a quote for 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42?
Yes, KEHONG BIO provides custom synthesis services for 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.