Propofol Hemisuccinate structure

Propofol Hemisuccinate

TL;DR: Propofol Hemisuccinate (CAS 184869-48-5) is a chemical compound with molecular formula C16H22O4 and molecular weight 278.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-[2,6-di(propan-2-yl)phenoxy]-4-oxobutanoic acid

Also Known As: Propofol hemisuccinate, Succinic acid monopropofol ester, 2,6-diisopropylphenyl hydrogen succinate, 4-[2,6-Di(propan-2-yl)phenoxy]-4-oxobutanoate, Butanedioic acid, 1-(2,6-bis(1-methylethyl)phenyl) ester

CAS: 184869-48-5
Molecular Formula C16H22O4
Molecular Weight 278.15 g/mol
LogP 3.7036
Topological Polar Surface Area 63.6 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 6
Exact Mass 278.1518
Heavy Atoms 20
Complexity 463.00027

Chemical Identifiers

CAS Number 184869-48-5
SMILES CC(C)C1=C(C(=CC=C1)C(C)C)OC(=O)CCC(=O)O

Product Overview

Propofol Hemisuccinate (CAS 184869-48-5), with molecular formula C16H22O4 and molecular weight 278.15 g/mol. IUPAC: 4-[2,6-di(propan-2-yl)phenoxy]-4-oxobutanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Propofol Hemisuccinate

XLogP
3.7036
TPSA (Topological Polar Surface Area)
63.6
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
6
Heavy Atoms
20
Complexity
463.00027
Exact Mass
278.1518
Monoisotopic Mass
278.1518
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Propofol Hemisuccinate

The XLogP value of 3.7036 indicates that Propofol Hemisuccinate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Propofol Hemisuccinate. Following Lipinski's Rule of Five, Propofol Hemisuccinate has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Propofol Hemisuccinate?

The CAS number of Propofol Hemisuccinate is 184869-48-5.

What is the molecular formula of Propofol Hemisuccinate?

The molecular formula of Propofol Hemisuccinate is C16H22O4.

What is the molecular weight of Propofol Hemisuccinate?

The molecular weight of Propofol Hemisuccinate is 278.15 g/mol.

Where can I buy Propofol Hemisuccinate?

You can request a quote for Propofol Hemisuccinate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Propofol Hemisuccinate?

Yes, KEHONG BIO provides custom synthesis services for Propofol Hemisuccinate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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