Bis(trimethylsilyl) malonate
TL;DR: Bis(trimethylsilyl) malonate (CAS 18457-04-0) is a chemical compound with molecular formula C9H20O4Si2 and molecular weight 248.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
bis(trimethylsilyl) propanedioate
Also Known As: Bis(trimethylsilyl) malonate, bis(trimethylsilyl) propanedioate, Malonic acid diTMS, Malonic acid (2TMS), Malonic acid, bis-TMS
| Molecular Formula | C9H20O4Si2 |
|---|---|
| Molecular Weight | 248.09 g/mol |
| LogP | 2.13 |
| Topological Polar Surface Area | 52.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 248.09001 |
| Heavy Atoms | 15 |
| Complexity | 224.0 |
Chemical Identifiers
| CAS Number | 18457-04-0 |
|---|---|
| SMILES | C[Si](C)(C)OC(=O)CC(=O)O[Si](C)(C)C |
| InChIKey | ATCKJLDGNXGLAO-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Bis(trimethylsilyl) malonate (CAS 18457-04-0), with molecular formula C9H20O4Si2 and molecular weight 248.09 g/mol. IUPAC: bis(trimethylsilyl) propanedioate.
Chemical Property Profile of Bis(trimethylsilyl) malonate
Property Insights of Bis(trimethylsilyl) malonate
The XLogP value of 2.13 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Bis(trimethylsilyl) malonate. With a topological polar surface area (TPSA) of 52.6 Ų, Bis(trimethylsilyl) malonate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Bis(trimethylsilyl) malonate has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Bis(trimethylsilyl) malonate?
The CAS number of Bis(trimethylsilyl) malonate is 18457-04-0.
What is the molecular formula of Bis(trimethylsilyl) malonate?
The molecular formula of Bis(trimethylsilyl) malonate is C9H20O4Si2.
What is the molecular weight of Bis(trimethylsilyl) malonate?
The molecular weight of Bis(trimethylsilyl) malonate is 248.09 g/mol.
Where can I buy Bis(trimethylsilyl) malonate?
You can request a quote for Bis(trimethylsilyl) malonate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Bis(trimethylsilyl) malonate?
Yes, KEHONG BIO provides custom synthesis services for Bis(trimethylsilyl) malonate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.