4-Fluoro-2'-hydroxychalcone
TL;DR: 4-Fluoro-2'-hydroxychalcone (CAS 1840-01-3) is a chemical compound with molecular formula C15H11FO2 and molecular weight 242.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(4-fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one
Also Known As: 4-fluoro-2'-hydroxychalcone, 3-(4-fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one, (2E)-3-(4-fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one
| Molecular Formula | C15H11FO2 |
|---|---|
| Molecular Weight | 242.07 g/mol |
| LogP | 3.4274 |
| Topological Polar Surface Area | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 242.07431 |
| Heavy Atoms | 18 |
| Complexity | 585.6975 |
Chemical Identifiers
| CAS Number | 1840-01-3 |
|---|---|
| SMILES | C1=CC=C(C(=C1)C(=O)C=CC2=CC=C(C=C2)F)O |
Product Overview
4-Fluoro-2'-hydroxychalcone (CAS 1840-01-3), with molecular formula C15H11FO2 and molecular weight 242.07 g/mol. IUPAC: 3-(4-fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one.
Chemical Property Profile of 4-Fluoro-2'-hydroxychalcone
Property Insights of 4-Fluoro-2'-hydroxychalcone
The XLogP value of 3.4274 indicates that 4-Fluoro-2'-hydroxychalcone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, 4-Fluoro-2'-hydroxychalcone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Fluoro-2'-hydroxychalcone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Fluoro-2'-hydroxychalcone?
The CAS number of 4-Fluoro-2'-hydroxychalcone is 1840-01-3.
What is the molecular formula of 4-Fluoro-2'-hydroxychalcone?
The molecular formula of 4-Fluoro-2'-hydroxychalcone is C15H11FO2.
What is the molecular weight of 4-Fluoro-2'-hydroxychalcone?
The molecular weight of 4-Fluoro-2'-hydroxychalcone is 242.07 g/mol.
Where can I buy 4-Fluoro-2'-hydroxychalcone?
You can request a quote for 4-Fluoro-2'-hydroxychalcone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Fluoro-2'-hydroxychalcone?
Yes, KEHONG BIO provides custom synthesis services for 4-Fluoro-2'-hydroxychalcone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.