2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline
TL;DR: 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline (CAS 18378-79-5) is a chemical compound with molecular formula C11H8F3NO and molecular weight 227.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-methyl-4-(trifluoromethyl)-1H-quinolin-2-one
Also Known As: 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline, 6-methyl-4-(trifluoromethyl)-1H-quinolin-2-one, 2(1H)-Quinolinone, 6-methyl-4-(trifluoromethyl)-, 5569AJ, 6-methyl-4-(trifluoromethyl)quinolin-2(1h)-one
| Molecular Formula | C11H8F3NO |
|---|---|
| Molecular Weight | 227.06 g/mol |
| LogP | 2.1 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 0 |
| Exact Mass | 227.0558 |
| Heavy Atoms | 16 |
| Complexity | 335.0 |
Chemical Identifiers
| CAS Number | 18378-79-5 |
|---|---|
| SMILES | CC1=CC2=C(C=C1)NC(=O)C=C2C(F)(F)F |
| InChIKey | KTJROJRNPOWDGG-UHFFFAOYSA-N |
Product Overview
2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline (CAS 18378-79-5), with molecular formula C11H8F3NO and molecular weight 227.06 g/mol. IUPAC: 6-methyl-4-(trifluoromethyl)-1H-quinolin-2-one.
Chemical Property Profile of 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline
Property Insights of 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline. With a topological polar surface area (TPSA) of 29.1 Ų, 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline?
The CAS number of 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline is 18378-79-5.
What is the molecular formula of 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline?
The molecular formula of 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline is C11H8F3NO.
What is the molecular weight of 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline?
The molecular weight of 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline is 227.06 g/mol.
Where can I buy 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline?
You can request a quote for 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline?
Yes, KEHONG BIO provides custom synthesis services for 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.