vincamine
TL;DR: vincamine (CAS 18374-18-0) is a chemical compound with molecular formula C21H26N2O3 and molecular weight 354.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl (15S,17S,19R)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate
Also Known As: vincamine, Isovincamine, trans-Vincamine, Vinpocetine Impurity M, Vinpocetine Impurity 18
| Molecular Formula | C21H26N2O3 |
|---|---|
| Molecular Weight | 354.19 g/mol |
| LogP | 2.9525 |
| Topological Polar Surface Area | 54.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 354.19434 |
| Heavy Atoms | 26 |
| Complexity | 904.0384 |
Chemical Identifiers
| CAS Number | 18374-18-0 |
|---|---|
| SMILES | CC[C@@]12CCCN3[C@H]1C4=C(CC3)C5=CC=CC=C5N4[C@](C2)(C(=O)OC)O |
Product Overview
vincamine (CAS 18374-18-0), with molecular formula C21H26N2O3 and molecular weight 354.19 g/mol. IUPAC: methyl (15S,17S,19R)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate.
Chemical Property Profile of vincamine
Property Insights of vincamine
The XLogP value of 2.9525 suggests moderate lipophilicity, balancing water solubility and membrane permeability for vincamine. With a topological polar surface area (TPSA) of 54.7 Ų, vincamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, vincamine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of vincamine?
The CAS number of vincamine is 18374-18-0.
What is the molecular formula of vincamine?
The molecular formula of vincamine is C21H26N2O3.
What is the molecular weight of vincamine?
The molecular weight of vincamine is 354.19 g/mol.
Where can I buy vincamine?
You can request a quote for vincamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for vincamine?
Yes, KEHONG BIO provides custom synthesis services for vincamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.