QH-II-66
TL;DR: QH-II-66 (CAS 183239-39-6) is a chemical compound with molecular formula C18H14N2O and molecular weight 274.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
QH-II-66
7-ethynyl-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one
Also Known As: PDSP1_001782, PDSP2_001765, 7-Ethynyl-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one, J1.266.944E, 2H-1,4-Benzodiazepin-2-one, 7-ethynyl-1,3-dihydro-1-methyl-5-phenyl-
| Molecular Formula | C18H14N2O |
|---|---|
| Molecular Weight | 274.11 g/mol |
| LogP | 2.4817 |
| Topological Polar Surface Area | 32.67 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 274.11063 |
| Heavy Atoms | 21 |
| Complexity | 769.5505 |
Chemical Identifiers
| CAS Number | 183239-39-6 |
|---|---|
| SMILES | CN1C(=O)CN=C(C2=C1C=CC(=C2)C#C)C3=CC=CC=C3 |
Product Overview
QH-II-66 (CAS 183239-39-6), with molecular formula C18H14N2O and molecular weight 274.11 g/mol. IUPAC: 7-ethynyl-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one.
Chemical Property Profile of QH-II-66
Property Insights of QH-II-66
The XLogP value of 2.4817 suggests moderate lipophilicity, balancing water solubility and membrane permeability for QH-II-66. With a topological polar surface area (TPSA) of 32.67 Ų, QH-II-66 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, QH-II-66 has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of QH-II-66?
The CAS number of QH-II-66 is 183239-39-6.
What is the molecular formula of QH-II-66?
The molecular formula of QH-II-66 is C18H14N2O.
What is the molecular weight of QH-II-66?
The molecular weight of QH-II-66 is 274.11 g/mol.
Where can I buy QH-II-66?
You can request a quote for QH-II-66 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for QH-II-66?
Yes, KEHONG BIO provides custom synthesis services for QH-II-66 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.