3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide structure

3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide

TL;DR: 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide (CAS 18303-52-1) is a chemical compound with molecular formula C27H46BrNO2 and molecular weight 495.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[(2S,3S,5S,10S,13S,17S)-3-hydroxy-10,13-dimethyl-2-(1-methylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone bromide

Also Known As: 1-(3-alpha-Hydroxy-20-oxo-5-alpha-pregnan-2-beta-yl)-1-methylpiperidinium bromide, 3-alpha-Hydroxy-2-beta-piperidino-5-alpha-pregnan-20-one methobromide, 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide, Piperidinium, 1-(3-alpha-hydroxy-20-oxo-5-alpha-pregnan-2-beta-yl)-1-methyl-, bromide, (8xi,9xi,14xi)-3alpha-Hydroxy-2beta-(1-methylpiperidin-1-ium-1-yl)-5alpha-pregnan-20-one bromide

CAS: 18303-52-1
Molecular Formula C27H46BrNO2
Molecular Weight 495.27 g/mol
LogP 2.2082
Topological Polar Surface Area 37.3 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 2
Exact Mass 495.27118
Heavy Atoms 31
Complexity 684.0

Chemical Identifiers

CAS Number 18303-52-1
SMILES CC(=O)[C@H]1CCC2[C@@]1(CCC3C2CC[C@@H]4[C@@]3(C[C@@H]([C@H](C4)O)[N+]5(CCCCC5)C)C)C.[Br-]
InChIKey QLIPMFYHYJPCDH-SKIXJUDISA-M

Product Overview

3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide (CAS 18303-52-1), with molecular formula C27H46BrNO2 and molecular weight 495.27 g/mol. IUPAC: 1-[(2S,3S,5S,10S,13S,17S)-3-hydroxy-10,13-dimethyl-2-(1-methylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone bromide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide

XLogP
2.2082
TPSA (Topological Polar Surface Area)
37.3
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
2
Heavy Atoms
31
Complexity
684.0
Exact Mass
495.27118
Monoisotopic Mass
495.27118
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide

The XLogP value of 2.2082 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide. With a topological polar surface area (TPSA) of 37.3 Ų, 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide?

The CAS number of 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide is 18303-52-1.

What is the molecular formula of 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide?

The molecular formula of 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide is C27H46BrNO2.

What is the molecular weight of 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide?

The molecular weight of 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide is 495.27 g/mol.

Where can I buy 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide?

You can request a quote for 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide?

Yes, KEHONG BIO provides custom synthesis services for 3-Hydroxy-2-(1-methylpiperidin-1-ium-1-yl)pregnan-20-one bromide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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