20-Hydroxypregn-4-en-3-one
TL;DR: 20-Hydroxypregn-4-en-3-one (CAS 18214-92-1) is a chemical compound with molecular formula C21H32O2 and molecular weight 316.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8S,9S,10R,13S,14S,17S)-17-(1-hydroxyethyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Also Known As: 20-Hydroxypregn-4-en-3-one, progesterone, 20-dihydroprogesterone, Dihydrogesterone, 20-hydroxy-4-pregnen-3-one
| Molecular Formula | C21H32O2 |
|---|---|
| Molecular Weight | 316.24 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 316.24023 |
| Heavy Atoms | 23 |
| Complexity | 550.0 |
Chemical Identifiers
| CAS Number | 18214-92-1 |
|---|---|
| SMILES | CC([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O |
| InChIKey | RWBRUCCWZPSBFC-HWSYHKBZSA-N |
Patent-Derived Application Labels
Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
20-Hydroxypregn-4-en-3-one (CAS 18214-92-1), with molecular formula C21H32O2 and molecular weight 316.24 g/mol. IUPAC: (8S,9S,10R,13S,14S,17S)-17-(1-hydroxyethyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 20-Hydroxypregn-4-en-3-one
Property Insights of 20-Hydroxypregn-4-en-3-one
The XLogP value of 4.2 indicates that 20-Hydroxypregn-4-en-3-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, 20-Hydroxypregn-4-en-3-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 20-Hydroxypregn-4-en-3-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 20-Hydroxypregn-4-en-3-one?
The CAS number of 20-Hydroxypregn-4-en-3-one is 18214-92-1.
What is the molecular formula of 20-Hydroxypregn-4-en-3-one?
The molecular formula of 20-Hydroxypregn-4-en-3-one is C21H32O2.
What is the molecular weight of 20-Hydroxypregn-4-en-3-one?
The molecular weight of 20-Hydroxypregn-4-en-3-one is 316.24 g/mol.
Where can I buy 20-Hydroxypregn-4-en-3-one?
You can request a quote for 20-Hydroxypregn-4-en-3-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 20-Hydroxypregn-4-en-3-one?
Yes, KEHONG BIO provides custom synthesis services for 20-Hydroxypregn-4-en-3-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.