6-alpha-Fluoro-16-alpha-methylprogesterone
TL;DR: 6-alpha-Fluoro-16-alpha-methylprogesterone (CAS 1818-56-0) is a chemical compound with molecular formula C22H31FO2 and molecular weight 346.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(6S,8S,9S,10R,13S,14S,16R,17S)-17-acetyl-6-fluoro-10,13,16-trimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Also Known As: 6-alpha-Fluoro-16-alpha-methylprogesterone, 6alpha-Fluoro-16alpha-methylpregn-4-ene-3,20-dione, 6-Fluoro-16-methylpregn-4-ene-3,20-dione, 6-alpha-Fluoro-16-alpha-methylpregn-4-ene-3,20-dione, Pregn-4-ene-3,20-dione, 6-alpha-fluoro-16-alpha-methyl-
| Molecular Formula | C22H31FO2 |
|---|---|
| Molecular Weight | 346.23 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 34.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 346.2308 |
| Heavy Atoms | 25 |
| Complexity | 652.0 |
Chemical Identifiers
| CAS Number | 1818-56-0 |
|---|---|
| SMILES | C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)CC[C@@]4([C@H]3CC[C@@]2([C@H]1C(=O)C)C)C)F |
| InChIKey | OFMUOMXAKXABEF-NDKKBYRMSA-N |
Product Overview
6-alpha-Fluoro-16-alpha-methylprogesterone (CAS 1818-56-0), with molecular formula C22H31FO2 and molecular weight 346.23 g/mol. IUPAC: (6S,8S,9S,10R,13S,14S,16R,17S)-17-acetyl-6-fluoro-10,13,16-trimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 6-alpha-Fluoro-16-alpha-methylprogesterone
Property Insights of 6-alpha-Fluoro-16-alpha-methylprogesterone
The XLogP value of 4.2 indicates that 6-alpha-Fluoro-16-alpha-methylprogesterone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.1 Ų, 6-alpha-Fluoro-16-alpha-methylprogesterone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-alpha-Fluoro-16-alpha-methylprogesterone has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-alpha-Fluoro-16-alpha-methylprogesterone?
The CAS number of 6-alpha-Fluoro-16-alpha-methylprogesterone is 1818-56-0.
What is the molecular formula of 6-alpha-Fluoro-16-alpha-methylprogesterone?
The molecular formula of 6-alpha-Fluoro-16-alpha-methylprogesterone is C22H31FO2.
What is the molecular weight of 6-alpha-Fluoro-16-alpha-methylprogesterone?
The molecular weight of 6-alpha-Fluoro-16-alpha-methylprogesterone is 346.23 g/mol.
Where can I buy 6-alpha-Fluoro-16-alpha-methylprogesterone?
You can request a quote for 6-alpha-Fluoro-16-alpha-methylprogesterone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-alpha-Fluoro-16-alpha-methylprogesterone?
Yes, KEHONG BIO provides custom synthesis services for 6-alpha-Fluoro-16-alpha-methylprogesterone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.