2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine structure

2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine

TL;DR: 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine (CAS 181785-94-4) is a chemical compound with molecular formula C9H9F2N3O3 and molecular weight 245.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-amino-5-fluoro-1-[(2R,5R)-4-fluoro-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidin-2-one

Also Known As: 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine, Cytidine, 2',3'-didehydro-2',3'-dideoxy-3',5-difluoro-, 5-Fluorocytidine, 2',3'-didehydro-2',3'-dideoxy-3'-fluoro-, 4-amino-5-fluoro-1-[(2R,5R)-4-fluoro-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidin-2-one, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5R)-4-fluoro-2,5-dihydro-5-(hydroxymethyl)-2-furanyl]-

CAS: 181785-94-4
Molecular Formula C9H9F2N3O3
Molecular Weight 245.06 g/mol
LogP -1.4
Topological Polar Surface Area 88.2 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 2
Exact Mass 245.0612
Heavy Atoms 17
Complexity 447.0

Chemical Identifiers

CAS Number 181785-94-4
SMILES C1=C([C@H](O[C@H]1N2C=C(C(=NC2=O)N)F)CO)F
InChIKey ZLPXROLFQUPNHI-RNFRBKRXSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (29 patents) Pharmaceutical Intermediates (21 patents)

Product Overview

2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine (CAS 181785-94-4), with molecular formula C9H9F2N3O3 and molecular weight 245.06 g/mol. IUPAC: 4-amino-5-fluoro-1-[(2R,5R)-4-fluoro-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidin-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine

XLogP
-1.4
TPSA (Topological Polar Surface Area)
88.2
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
2
Heavy Atoms
17
Complexity
447.0
Exact Mass
245.0612
Monoisotopic Mass
245.0612
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine

The XLogP value of -1.4 indicates that 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 88.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine. Following Lipinski's Rule of Five, 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine?

The CAS number of 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine is 181785-94-4.

What is the molecular formula of 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine?

The molecular formula of 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine is C9H9F2N3O3.

What is the molecular weight of 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine?

The molecular weight of 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine is 245.06 g/mol.

Where can I buy 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine?

You can request a quote for 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine?

Yes, KEHONG BIO provides custom synthesis services for 2',3'-Didehydro-2',3'-dideoxy-3',5-difluoroCytidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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