Acotiamide hydrochloride
TL;DR: Acotiamide hydrochloride (CAS 1809272-85-2) is a chemical compound with molecular formula C21H31ClN4O5S and molecular weight 486.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-[di(propan-2-yl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-1,3-thiazole-4-carboxamide;hydrochloride
Also Known As: Acotiamide hydrochloride, Acotiamide HCl, Acotiamide D6, Acotiamide Impurity 28, Acotiamidehydrochloride
| Molecular Formula | C21H31ClN4O5S |
|---|---|
| Molecular Weight | 486.17 g/mol |
| LogP | 3.3886 |
| Topological Polar Surface Area | 113.02 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 10 |
| Exact Mass | 486.17038 |
| Heavy Atoms | 32 |
| Complexity | 911.59015 |
Chemical Identifiers
| CAS Number | 1809272-85-2 |
|---|---|
| SMILES | CC(C)N(CCNC(=O)C1=CSC(=N1)NC(=O)C2=CC(=C(C=C2O)OC)OC)C(C)C.Cl |
Product Overview
Acotiamide hydrochloride (CAS 1809272-85-2), with molecular formula C21H31ClN4O5S and molecular weight 486.17 g/mol. IUPAC: N-[2-[di(propan-2-yl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-1,3-thiazole-4-carboxamide;hydrochloride.
Chemical Property Profile of Acotiamide hydrochloride
Property Insights of Acotiamide hydrochloride
The XLogP value of 3.3886 indicates that Acotiamide hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 113.02 Ų falls within the moderate polarity range, balancing permeability and solubility for Acotiamide hydrochloride. Following Lipinski's Rule of Five, Acotiamide hydrochloride has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Acotiamide hydrochloride?
The CAS number of Acotiamide hydrochloride is 1809272-85-2.
What is the molecular formula of Acotiamide hydrochloride?
The molecular formula of Acotiamide hydrochloride is C21H31ClN4O5S.
What is the molecular weight of Acotiamide hydrochloride?
The molecular weight of Acotiamide hydrochloride is 486.17 g/mol.
Where can I buy Acotiamide hydrochloride?
You can request a quote for Acotiamide hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Acotiamide hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Acotiamide hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.