Lasofoxifene
TL;DR: Lasofoxifene (CAS 180915-85-9) is a chemical compound with molecular formula C28H31NO2 and molecular weight 413.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
Also Known As: Lasofoxifene, rac-Lasofoxifene, Oporia, lasofoxifeno, lasofoxifenum
| Molecular Formula | C28H31NO2 |
|---|---|
| Molecular Weight | 413.24 g/mol |
| LogP | 6.1 |
| Topological Polar Surface Area | 32.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 6 |
| Exact Mass | 413.23547 |
| Heavy Atoms | 31 |
| Complexity | 533.0 |
Chemical Identifiers
| CAS Number | 180915-85-9 |
|---|---|
| SMILES | C1CCN(C1)CCOC2=CC=C(C=C2)[C@H]3[C@H](CCC4=C3C=CC(=C4)O)C5=CC=CC=C5 |
| InChIKey | GXESHMAMLJKROZ-IAPPQJPRSA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Lasofoxifene (CAS 180915-85-9), with molecular formula C28H31NO2 and molecular weight 413.24 g/mol. IUPAC: (5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol.
Chemical Property Profile of Lasofoxifene
Property Insights of Lasofoxifene
The XLogP value of 6.1 indicates that Lasofoxifene is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.7 Ų, Lasofoxifene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Lasofoxifene has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lasofoxifene?
The CAS number of Lasofoxifene is 180915-85-9.
What is the molecular formula of Lasofoxifene?
The molecular formula of Lasofoxifene is C28H31NO2.
What is the molecular weight of Lasofoxifene?
The molecular weight of Lasofoxifene is 413.24 g/mol.
Where can I buy Lasofoxifene?
You can request a quote for Lasofoxifene directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lasofoxifene?
Yes, KEHONG BIO provides custom synthesis services for Lasofoxifene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.