3beta-Hydroxy-16-methylpregna-5,16-dien-20-one structure

3beta-Hydroxy-16-methylpregna-5,16-dien-20-one

TL;DR: 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one (CAS 1808-63-5) is a chemical compound with molecular formula C22H32O2 and molecular weight 328.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[(3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13,16-trimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone

Also Known As: 16-methyl-16-Pregnenolone, 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one, 16-METHYL-16-DEHYDROPREGNENOLONE, 3-Hydroxy-16-methylpregna-5,16-dien-20-one, 5,16-Pregnadien-16-methyl-3beta-ol-20-one

CAS: 1808-63-5
Molecular Formula C22H32O2
Molecular Weight 328.24 g/mol
LogP 3.8
Topological Polar Surface Area 37.3 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 328.24023
Heavy Atoms 24
Complexity 642.0

Chemical Identifiers

CAS Number 1808-63-5
SMILES CC1=C([C@]2(CC[C@H]3[C@H]([C@@H]2C1)CC=C4[C@@]3(CC[C@@H](C4)O)C)C)C(=O)C
InChIKey WYOKDIKHIXWWOC-LXIBVNSESA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (9 patents) Pharmaceutical Intermediates (5 patents)

Product Overview

3beta-Hydroxy-16-methylpregna-5,16-dien-20-one (CAS 1808-63-5), with molecular formula C22H32O2 and molecular weight 328.24 g/mol. IUPAC: 1-[(3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13,16-trimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one

XLogP
3.8
TPSA (Topological Polar Surface Area)
37.3
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
24
Complexity
642.0
Exact Mass
328.24023
Monoisotopic Mass
328.24023
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one

The XLogP value of 3.8 indicates that 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one?

The CAS number of 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one is 1808-63-5.

What is the molecular formula of 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one?

The molecular formula of 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one is C22H32O2.

What is the molecular weight of 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one?

The molecular weight of 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one is 328.24 g/mol.

Where can I buy 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one?

You can request a quote for 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one?

Yes, KEHONG BIO provides custom synthesis services for 3beta-Hydroxy-16-methylpregna-5,16-dien-20-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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