Tezosentan disodium
TL;DR: Tezosentan disodium (CAS 180384-58-1) is a chemical compound with molecular formula C27H25N9Na2O6S and molecular weight 649.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
disodium;[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)-4-pyridinyl]pyrimidin-4-yl]-[(5-propan-2-yl-2-pyridinyl)sulfonyl]azanide
Also Known As: Tezosentan disodium, Veletri, Tazosentan, Tezosentan, Veletri (TN)
| Molecular Formula | C27H25N9Na2O6S |
|---|---|
| Molecular Weight | 649.14 g/mol |
| LogP | -2.5597 |
| Topological Polar Surface Area | 200.49 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 13 |
| Rotatable Bonds | 12 |
| Exact Mass | 649.1444 |
| Heavy Atoms | 45 |
| Complexity | 1812.5393 |
Chemical Identifiers
| CAS Number | 180384-58-1 |
|---|---|
| SMILES | CC(C)C1=CN=C(C=C1)S(=O)(=O)[N-]C2=C(C(=NC(=N2)C3=CC(=NC=C3)C4=NN=N[N-]4)OCCO)OC5=CC=CC=C5OC.[Na+].[Na+] |
Product Overview
Tezosentan disodium (CAS 180384-58-1), with molecular formula C27H25N9Na2O6S and molecular weight 649.14 g/mol. IUPAC: disodium;[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)-4-pyridinyl]pyrimidin-4-yl]-[(5-propan-2-yl-2-pyridinyl)sulfonyl]azanide.
Chemical Property Profile of Tezosentan disodium
Property Insights of Tezosentan disodium
The XLogP value of -2.5597 indicates that Tezosentan disodium is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 200.49 Ų indicates high polarity, suggesting Tezosentan disodium may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tezosentan disodium has 1 hydrogen bond donor(s) and 13 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tezosentan disodium?
The CAS number of Tezosentan disodium is 180384-58-1.
What is the molecular formula of Tezosentan disodium?
The molecular formula of Tezosentan disodium is C27H25N9Na2O6S.
What is the molecular weight of Tezosentan disodium?
The molecular weight of Tezosentan disodium is 649.14 g/mol.
Where can I buy Tezosentan disodium?
You can request a quote for Tezosentan disodium directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tezosentan disodium?
Yes, KEHONG BIO provides custom synthesis services for Tezosentan disodium and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.