Clazosentan
TL;DR: Clazosentan (CAS 180384-56-9) is a chemical compound with molecular formula C25H23N9O6S and molecular weight 577.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridinyl]pyrimidin-4-yl]-5-methylpyridine-2-sulfonamide
Also Known As: Clazosentan, Pivlaz, clazosentanum, Clazosentan [INN], CLAZOSENTAN [MI]
| Molecular Formula | C25H23N9O6S |
|---|---|
| Molecular Weight | 577.15 g/mol |
| LogP | 2.39492 |
| Topological Polar Surface Area | 200.11 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 13 |
| Rotatable Bonds | 11 |
| Exact Mass | 577.14923 |
| Heavy Atoms | 41 |
| Complexity | 1750.4534 |
Chemical Identifiers
| CAS Number | 180384-56-9 |
|---|---|
| SMILES | CC1=CN=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=CC(=NC=C3)C4=NNN=N4)OCCO)OC5=CC=CC=C5OC |
Product Overview
Clazosentan (CAS 180384-56-9), with molecular formula C25H23N9O6S and molecular weight 577.15 g/mol. IUPAC: N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridinyl]pyrimidin-4-yl]-5-methylpyridine-2-sulfonamide.
Chemical Property Profile of Clazosentan
Property Insights of Clazosentan
The XLogP value of 2.39492 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Clazosentan. The TPSA of 200.11 Ų indicates high polarity, suggesting Clazosentan may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Clazosentan has 3 hydrogen bond donor(s) and 13 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Clazosentan?
The CAS number of Clazosentan is 180384-56-9.
What is the molecular formula of Clazosentan?
The molecular formula of Clazosentan is C25H23N9O6S.
What is the molecular weight of Clazosentan?
The molecular weight of Clazosentan is 577.15 g/mol.
Where can I buy Clazosentan?
You can request a quote for Clazosentan directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Clazosentan?
Yes, KEHONG BIO provides custom synthesis services for Clazosentan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.