Lotrafiban Hydrochloride structure

Lotrafiban Hydrochloride

TL;DR: Lotrafiban Hydrochloride (CAS 179599-82-7) is a chemical compound with molecular formula C23H33ClN4O4 and molecular weight 464.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[(2S)-4-methyl-3-oxo-7-(4-piperidin-4-ylpiperidine-1-carbonyl)-2,5-dihydro-1H-1,4-benzodiazepin-2-yl]acetic acid;hydrochloride

Also Known As: Lotrafiban hydrochloride, Lotrafiban HCl, Lotrafiban (hydrochloride), Lotrafiban hydrochloride [USAN], Lotrafiban hydrochloride (USAN)

CAS: 179599-82-7
Molecular Formula C23H33ClN4O4
Molecular Weight 464.22 g/mol
LogP 2.19
Topological Polar Surface Area 102.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 6
Rotatable Bonds 4
Exact Mass 464.21902
Heavy Atoms 32
Complexity 672.0

Chemical Identifiers

CAS Number 179599-82-7
SMILES CN1CC2=C(C=CC(=C2)C(=O)N3CCC(CC3)C4CCNCC4)N[C@H](C1=O)CC(=O)O.Cl
InChIKey ZTHSAEXVSBEBHE-BDQAORGHSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (20 patents) Pharmaceutical Intermediates (130 patents)

Product Overview

Lotrafiban Hydrochloride (CAS 179599-82-7), with molecular formula C23H33ClN4O4 and molecular weight 464.22 g/mol. IUPAC: 2-[(2S)-4-methyl-3-oxo-7-(4-piperidin-4-ylpiperidine-1-carbonyl)-2,5-dihydro-1H-1,4-benzodiazepin-2-yl]acetic acid;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Lotrafiban Hydrochloride

XLogP
2.19
TPSA (Topological Polar Surface Area)
102.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
6
Rotatable Bonds
4
Heavy Atoms
32
Complexity
672.0
Exact Mass
464.21902
Monoisotopic Mass
464.21902
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Lotrafiban Hydrochloride

The XLogP value of 2.19 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Lotrafiban Hydrochloride. The TPSA of 102.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Lotrafiban Hydrochloride. Following Lipinski's Rule of Five, Lotrafiban Hydrochloride has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Lotrafiban Hydrochloride?

The CAS number of Lotrafiban Hydrochloride is 179599-82-7.

What is the molecular formula of Lotrafiban Hydrochloride?

The molecular formula of Lotrafiban Hydrochloride is C23H33ClN4O4.

What is the molecular weight of Lotrafiban Hydrochloride?

The molecular weight of Lotrafiban Hydrochloride is 464.22 g/mol.

Where can I buy Lotrafiban Hydrochloride?

You can request a quote for Lotrafiban Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Lotrafiban Hydrochloride?

Yes, KEHONG BIO provides custom synthesis services for Lotrafiban Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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