N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan
TL;DR: N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan (CAS 179545-77-8) is a chemical compound with molecular formula C23H34N3O10P and molecular weight 543.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-[[(2S)-2-[[hydroxy-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyphosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
Also Known As: Talopeptin, phosphoramidon, talopeptin (MKI), N-(6-deoxy-alpha-talopyranosyloxyphospho)-leucyl-tryptophan, (2S)-2-[[(2S)-2-[[hydroxy-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyphosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
| Molecular Formula | C23H34N3O10P |
|---|---|
| Molecular Weight | 543.20 g/mol |
| LogP | -0.2 |
| Topological Polar Surface Area | 211.0 Ų |
| Hydrogen Bond Donors | 8 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 11 |
| Exact Mass | 543.1982 |
| Heavy Atoms | 37 |
| Complexity | 848.0 |
Chemical Identifiers
| CAS Number | 179545-77-8 |
|---|---|
| SMILES | C[C@H]1[C@H]([C@H]([C@H]([C@@H](O1)OP(=O)(N[C@@H](CC(C)C)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)O)O)O)O)O |
| InChIKey | ZPHBZEQOLSRPAK-XVOJFHBISA-N |
Product Overview
N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan (CAS 179545-77-8), with molecular formula C23H34N3O10P and molecular weight 543.20 g/mol. IUPAC: (2S)-2-[[(2S)-2-[[hydroxy-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyphosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid.
Chemical Property Profile of N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan
Property Insights of N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan
The XLogP value of -0.2 indicates that N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 211.0 Ų indicates high polarity, suggesting N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan has 8 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan?
The CAS number of N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan is 179545-77-8.
What is the molecular formula of N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan?
The molecular formula of N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan is C23H34N3O10P.
What is the molecular weight of N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan?
The molecular weight of N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan is 543.20 g/mol.
Where can I buy N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan?
You can request a quote for N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan?
Yes, KEHONG BIO provides custom synthesis services for N-(((6-Deoxy-alpha-L-talopyranosyl)oxy)hydroxyphosphinyl)-L-leucyl-L-tryptophan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.