Prucalopride hydrochloride
TL;DR: Prucalopride hydrochloride (CAS 179474-80-7) is a chemical compound with molecular formula C18H27Cl2N3O3 and molecular weight 403.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide;hydrochloride
Also Known As: Prucalopride hydrochloride, Prucalopride (hydrochloride), PRUCALOPRIDE HYDROCHLORIDE [MART.], PRUCALOPRIDE HYDROCHLORIDE [WHO-DD], 179474-80-7 (HCl)
| Molecular Formula | C18H27Cl2N3O3 |
|---|---|
| Molecular Weight | 403.14 g/mol |
| LogP | 2.5096 |
| Topological Polar Surface Area | 76.82 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 403.14294 |
| Heavy Atoms | 26 |
| Complexity | 634.5976 |
Chemical Identifiers
| CAS Number | 179474-80-7 |
|---|---|
| SMILES | COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl.Cl |
Product Overview
Prucalopride hydrochloride (CAS 179474-80-7), with molecular formula C18H27Cl2N3O3 and molecular weight 403.14 g/mol. IUPAC: 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide;hydrochloride.
Chemical Property Profile of Prucalopride hydrochloride
Property Insights of Prucalopride hydrochloride
The XLogP value of 2.5096 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Prucalopride hydrochloride. The TPSA of 76.82 Ų falls within the moderate polarity range, balancing permeability and solubility for Prucalopride hydrochloride. Following Lipinski's Rule of Five, Prucalopride hydrochloride has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Prucalopride hydrochloride?
The CAS number of Prucalopride hydrochloride is 179474-80-7.
What is the molecular formula of Prucalopride hydrochloride?
The molecular formula of Prucalopride hydrochloride is C18H27Cl2N3O3.
What is the molecular weight of Prucalopride hydrochloride?
The molecular weight of Prucalopride hydrochloride is 403.14 g/mol.
Where can I buy Prucalopride hydrochloride?
You can request a quote for Prucalopride hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Prucalopride hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Prucalopride hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.