floxuridine
TL;DR: floxuridine (CAS 179239-85-1) is a chemical compound with molecular formula C9H11FN2O5 and molecular weight 246.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-fluoro-1-[(2R,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Also Known As: floxuridine, 1-(2-Deoxy-, A-L-erythro-pentofuranosyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione, 5-fluoro-1-[(2R,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione, 1-(2-Deoxy-
| Molecular Formula | C9H11FN2O5 |
|---|---|
| Molecular Weight | 246.07 g/mol |
| LogP | -1.6836 |
| Topological Polar Surface Area | 104.55 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 246.0652 |
| Heavy Atoms | 17 |
| Complexity | 524.8529 |
Chemical Identifiers
| CAS Number | 179239-85-1 |
|---|---|
| SMILES | C1[C@H]([C@@H](O[C@H]1N2C=C(C(=O)NC2=O)F)CO)O |
Product Overview
floxuridine (CAS 179239-85-1), with molecular formula C9H11FN2O5 and molecular weight 246.07 g/mol. IUPAC: 5-fluoro-1-[(2R,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione.
Chemical Property Profile of floxuridine
Property Insights of floxuridine
The XLogP value of -1.6836 indicates that floxuridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 104.55 Ų falls within the moderate polarity range, balancing permeability and solubility for floxuridine. Following Lipinski's Rule of Five, floxuridine has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of floxuridine?
The CAS number of floxuridine is 179239-85-1.
What is the molecular formula of floxuridine?
The molecular formula of floxuridine is C9H11FN2O5.
What is the molecular weight of floxuridine?
The molecular weight of floxuridine is 246.07 g/mol.
Where can I buy floxuridine?
You can request a quote for floxuridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for floxuridine?
Yes, KEHONG BIO provides custom synthesis services for floxuridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.