Lenapenem
TL;DR: Lenapenem (CAS 178980-01-3) is a chemical compound with molecular formula C18H29N3O5S and molecular weight 399.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-3-[(3S,5S)-5-[(1R)-1-hydroxy-3-(methylamino)propyl]pyrrolidin-3-yl]sulfanyl-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Also Known As: Lenapenem, Lenapenem [INN], KST-1A2125, BO 2727, (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-3-[(3S,5S)-5-[(1R)-1-hydroxy-3-(methylamino)propyl]pyrrolidin-3-yl]sulfanyl-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
| Molecular Formula | C18H29N3O5S |
|---|---|
| Molecular Weight | 399.18 g/mol |
| LogP | -2.5 |
| Topological Polar Surface Area | 147.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 8 |
| Exact Mass | 399.1828 |
| Heavy Atoms | 27 |
| Complexity | 642.0 |
Chemical Identifiers
| CAS Number | 178980-01-3 |
|---|---|
| SMILES | C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)[C@@H](CCNC)O)C(=O)O)[C@@H](C)O |
| InChIKey | PZLOCBSBEUDCPF-YJIVIRPOSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Lenapenem (CAS 178980-01-3), with molecular formula C18H29N3O5S and molecular weight 399.18 g/mol. IUPAC: (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-3-[(3S,5S)-5-[(1R)-1-hydroxy-3-(methylamino)propyl]pyrrolidin-3-yl]sulfanyl-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid.
Chemical Property Profile of Lenapenem
Property Insights of Lenapenem
The XLogP value of -2.5 indicates that Lenapenem is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 147.0 Ų indicates high polarity, suggesting Lenapenem may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Lenapenem has 5 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lenapenem?
The CAS number of Lenapenem is 178980-01-3.
What is the molecular formula of Lenapenem?
The molecular formula of Lenapenem is C18H29N3O5S.
What is the molecular weight of Lenapenem?
The molecular weight of Lenapenem is 399.18 g/mol.
Where can I buy Lenapenem?
You can request a quote for Lenapenem directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lenapenem?
Yes, KEHONG BIO provides custom synthesis services for Lenapenem and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.