DZ 3358
TL;DR: DZ 3358 (CAS 178927-85-0) is a chemical compound with molecular formula C21H24Cl2N6 and molecular weight 430.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-[(E)-3-[4-(3-chlorophenyl)piperazin-1-yl]prop-1-enyl]-5-methylpyrazol-1-yl]pyrimidine;hydrochloride
Also Known As: DZ 3358, 1-(3-Chlorophenyl)-4-(3-(5-methyl-1-(2-pyrimidinyl)pyrazol-4-yl)-1(E)-propenyl)piperazine hydrochloride, 2-(4-((1E)-3-(4-(3-Chlorophenyl)piperazin-1-yl)prop-1-en-1-yl)-5-methyl-1H-pyrazol-1-yl)pyrimidine hydrochloride, Pyrimidine, 2-(4-((1E)-3-(4-(3-chlorophenyl)-1-piperazinyl)-1-propenyl)-5-methyl-1H-pyrazol-1-yl)-, monohydrochloride, Pyrimidine, 2-(4-(3-(4-(3-chlorophenyl)-1-piperazinyl)-1-propenyl)-5-methyl-1H-pyrazol-1-yl)-, monohydrochloride, (E)-
| Molecular Formula | C21H24Cl2N6 |
|---|---|
| Molecular Weight | 430.14 g/mol |
| LogP | 3.88132 |
| Topological Polar Surface Area | 50.08 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 430.14395 |
| Heavy Atoms | 29 |
| Complexity | 948.815 |
Chemical Identifiers
| CAS Number | 178927-85-0 |
|---|---|
| SMILES | CC1=C(C=NN1C2=NC=CC=N2)/C=C/CN3CCN(CC3)C4=CC(=CC=C4)Cl.Cl |
Product Overview
DZ 3358 (CAS 178927-85-0), with molecular formula C21H24Cl2N6 and molecular weight 430.14 g/mol. IUPAC: 2-[4-[(E)-3-[4-(3-chlorophenyl)piperazin-1-yl]prop-1-enyl]-5-methylpyrazol-1-yl]pyrimidine;hydrochloride.
Chemical Property Profile of DZ 3358
Property Insights of DZ 3358
The XLogP value of 3.88132 indicates that DZ 3358 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.08 Ų, DZ 3358 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, DZ 3358 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of DZ 3358?
The CAS number of DZ 3358 is 178927-85-0.
What is the molecular formula of DZ 3358?
The molecular formula of DZ 3358 is C21H24Cl2N6.
What is the molecular weight of DZ 3358?
The molecular weight of DZ 3358 is 430.14 g/mol.
Where can I buy DZ 3358?
You can request a quote for DZ 3358 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for DZ 3358?
Yes, KEHONG BIO provides custom synthesis services for DZ 3358 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.