Darusentan, (+/-)-
TL;DR: Darusentan, (+/-)- (CAS 178306-46-2) is a chemical compound with molecular formula C22H22N2O6 and molecular weight 410.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4,6-dimethoxypyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid
Also Known As: Darusentan, Darusentan, (+/-)-, Darusentan, (RS)-, (+/-)-darusentan, Darusentan (+/-)-form [MI]
| Molecular Formula | C22H22N2O6 |
|---|---|
| Molecular Weight | 410.15 g/mol |
| LogP | 2.916 |
| Topological Polar Surface Area | 100.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 9 |
| Exact Mass | 410.1478 |
| Heavy Atoms | 30 |
| Complexity | 919.6826 |
Chemical Identifiers
| CAS Number | 178306-46-2 |
|---|---|
| SMILES | COC1=CC(=NC(=N1)OC(C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)OC |
Product Overview
Darusentan, (+/-)- (CAS 178306-46-2), with molecular formula C22H22N2O6 and molecular weight 410.15 g/mol. IUPAC: 2-(4,6-dimethoxypyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid.
Chemical Property Profile of Darusentan, (+/-)-
Property Insights of Darusentan, (+/-)-
The XLogP value of 2.916 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Darusentan, (+/-)-. The TPSA of 100.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Darusentan, (+/-)-. Following Lipinski's Rule of Five, Darusentan, (+/-)- has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Darusentan, (+/-)-?
The CAS number of Darusentan, (+/-)- is 178306-46-2.
What is the molecular formula of Darusentan, (+/-)-?
The molecular formula of Darusentan, (+/-)- is C22H22N2O6.
What is the molecular weight of Darusentan, (+/-)-?
The molecular weight of Darusentan, (+/-)- is 410.15 g/mol.
Where can I buy Darusentan, (+/-)-?
You can request a quote for Darusentan, (+/-)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Darusentan, (+/-)-?
Yes, KEHONG BIO provides custom synthesis services for Darusentan, (+/-)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.