SB 243213
TL;DR: SB 243213 (CAS 1780372-25-9) is a chemical compound with molecular formula C22H19F3N4O2 and molecular weight 428.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Also Known As: sb 243213 dihydrochloride, starbld0000862, SB-243213 free base, Pazopanib + Tyverb/Tykerb, SB 243213 (hydrochloride)
| Molecular Formula | C22H19F3N4O2 |
|---|---|
| Molecular Weight | 428.15 g/mol |
| LogP | 4.1 |
| Topological Polar Surface Area | 67.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 428.146 |
| Heavy Atoms | 31 |
| Complexity | 634.0 |
Chemical Identifiers
| CAS Number | 1780372-25-9 |
|---|---|
| SMILES | CC1=CC2=C(C=C1C(F)(F)F)N(CC2)C(=O)NC3=CN=C(C=C3)OC4=C(N=CC=C4)C |
| InChIKey | ZETBBVYSBABLHL-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
SB 243213 (CAS 1780372-25-9), with molecular formula C22H19F3N4O2 and molecular weight 428.15 g/mol. IUPAC: 5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide.
Chemical Property Profile of SB 243213
Property Insights of SB 243213
The XLogP value of 4.1 indicates that SB 243213 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.4 Ų falls within the moderate polarity range, balancing permeability and solubility for SB 243213. Following Lipinski's Rule of Five, SB 243213 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of SB 243213?
The CAS number of SB 243213 is 1780372-25-9.
What is the molecular formula of SB 243213?
The molecular formula of SB 243213 is C22H19F3N4O2.
What is the molecular weight of SB 243213?
The molecular weight of SB 243213 is 428.15 g/mol.
Where can I buy SB 243213?
You can request a quote for SB 243213 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for SB 243213?
Yes, KEHONG BIO provides custom synthesis services for SB 243213 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.