Sarizotan
TL;DR: Sarizotan (CAS 177975-08-5) is a chemical compound with molecular formula C22H21FN2O and molecular weight 348.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R)-3,4-dihydro-2H-chromen-2-yl]-N-[[5-(4-fluorophenyl)-3-pyridinyl]methyl]methanamine
Also Known As: Sarizotan, Sarizotan [INN], sarizotanum, Sarizotan (Standard), SARIZOTAN [MI]
| Molecular Formula | C22H21FN2O |
|---|---|
| Molecular Weight | 348.16 g/mol |
| LogP | 4.3711 |
| Topological Polar Surface Area | 34.15 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 348.1638 |
| Heavy Atoms | 26 |
| Complexity | 879.32056 |
Chemical Identifiers
| CAS Number | 177975-08-5 |
|---|---|
| SMILES | C1CC2=CC=CC=C2O[C@H]1CNCC3=CC(=CN=C3)C4=CC=C(C=C4)F |
Product Overview
Sarizotan (CAS 177975-08-5), with molecular formula C22H21FN2O and molecular weight 348.16 g/mol. IUPAC: 1-[(2R)-3,4-dihydro-2H-chromen-2-yl]-N-[[5-(4-fluorophenyl)-3-pyridinyl]methyl]methanamine.
Chemical Property Profile of Sarizotan
Property Insights of Sarizotan
The XLogP value of 4.3711 indicates that Sarizotan is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.15 Ų, Sarizotan exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Sarizotan has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Sarizotan?
The CAS number of Sarizotan is 177975-08-5.
What is the molecular formula of Sarizotan?
The molecular formula of Sarizotan is C22H21FN2O.
What is the molecular weight of Sarizotan?
The molecular weight of Sarizotan is 348.16 g/mol.
Where can I buy Sarizotan?
You can request a quote for Sarizotan directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Sarizotan?
Yes, KEHONG BIO provides custom synthesis services for Sarizotan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.