Tezacitabine
TL;DR: Tezacitabine (CAS 177956-36-4) is a chemical compound with molecular formula C10H12FN3O4 and molecular weight 257.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-1-[(2R,3E,4S,5R)-3-(fluoromethylidene)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Also Known As: Tezacitabine, tezaciabine, tezacitabina, Fmdc cpd, anhydrous
| Molecular Formula | C10H12FN3O4 |
|---|---|
| Molecular Weight | 257.08 g/mol |
| LogP | -1.0705 |
| Topological Polar Surface Area | 110.6 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 257.08118 |
| Heavy Atoms | 18 |
| Complexity | 530.09924 |
Chemical Identifiers
| CAS Number | 177956-36-4 |
|---|---|
| SMILES | C1=CN(C(=O)N=C1N)[C@H]2/C(=C/F)/[C@@H]([C@H](O2)CO)O |
Product Overview
Tezacitabine (CAS 177956-36-4), with molecular formula C10H12FN3O4 and molecular weight 257.08 g/mol. IUPAC: 4-amino-1-[(2R,3E,4S,5R)-3-(fluoromethylidene)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one.
Chemical Property Profile of Tezacitabine
Property Insights of Tezacitabine
The XLogP value of -1.0705 indicates that Tezacitabine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 110.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Tezacitabine. Following Lipinski's Rule of Five, Tezacitabine has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tezacitabine?
The CAS number of Tezacitabine is 177956-36-4.
What is the molecular formula of Tezacitabine?
The molecular formula of Tezacitabine is C10H12FN3O4.
What is the molecular weight of Tezacitabine?
The molecular weight of Tezacitabine is 257.08 g/mol.
Where can I buy Tezacitabine?
You can request a quote for Tezacitabine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tezacitabine?
Yes, KEHONG BIO provides custom synthesis services for Tezacitabine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.