Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide
TL;DR: Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide (CAS 177080-77-2) is a chemical compound with molecular formula C28H43N9O6 and molecular weight 601.33 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-N-[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]-5-oxopyrrolidine-2-carboxamide
Also Known As: Pglu-leu-gly-arg-phe-amide, Pglu-leu-gly-arg-phe-NH2, Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide, 3-(3,4-dimethoxyphenyl)propanamide, J2.405.093I
| Molecular Formula | C28H43N9O6 |
|---|---|
| Molecular Weight | 601.33 g/mol |
| LogP | -1.1 |
| Topological Polar Surface Area | 253.0 Ų |
| Hydrogen Bond Donors | 8 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 17 |
| Exact Mass | 601.3336 |
| Heavy Atoms | 43 |
| Complexity | 1020.0 |
Chemical Identifiers
| CAS Number | 177080-77-2 |
|---|---|
| SMILES | CC(C)C[C@@H](C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)NC(=O)[C@@H]2CCC(=O)N2 |
| InChIKey | JOJUNHUHLMUZOG-TUFLPTIASA-N |
Product Overview
Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide (CAS 177080-77-2), with molecular formula C28H43N9O6 and molecular weight 601.33 g/mol. IUPAC: (2S)-N-[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]-5-oxopyrrolidine-2-carboxamide.
Chemical Property Profile of Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide
Property Insights of Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide
The XLogP value of -1.1 indicates that Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 253.0 Ų indicates high polarity, suggesting Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide has 8 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide?
The CAS number of Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide is 177080-77-2.
What is the molecular formula of Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide?
The molecular formula of Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide is C28H43N9O6.
What is the molecular weight of Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide?
The molecular weight of Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide is 601.33 g/mol.
Where can I buy Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide?
You can request a quote for Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide?
Yes, KEHONG BIO provides custom synthesis services for Pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.