ICI U24522
TL;DR: ICI U24522 (CAS 176776-68-4) is a chemical compound with molecular formula C23H36N4O5 and molecular weight 448.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R)-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide
Also Known As: ICI U24522, N-{(2r)-2-[2-(Hydroxyamino)-2-Oxoethyl]-4-Methylpentanoyl}-L-Leucyl-L-Phenylalaninamide, (R)-N*1*-[(S)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-3-methyl-butyl]-N*4*-hydroxy-2-isobutyl-succinamide, 0DS, L-Phenylalaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-L-leucyl-
| Molecular Formula | C23H36N4O5 |
|---|---|
| Molecular Weight | 448.27 g/mol |
| LogP | 1.2879 |
| Topological Polar Surface Area | 150.62 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 13 |
| Exact Mass | 448.2686 |
| Heavy Atoms | 32 |
| Complexity | 766.9101 |
Chemical Identifiers
| CAS Number | 176776-68-4 |
|---|---|
| SMILES | CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N |
Product Overview
ICI U24522 (CAS 176776-68-4), with molecular formula C23H36N4O5 and molecular weight 448.27 g/mol. IUPAC: (2R)-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide.
Chemical Property Profile of ICI U24522
Property Insights of ICI U24522
The XLogP value of 1.2879 suggests moderate lipophilicity, balancing water solubility and membrane permeability for ICI U24522. The TPSA of 150.62 Ų indicates high polarity, suggesting ICI U24522 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, ICI U24522 has 5 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of ICI U24522?
The CAS number of ICI U24522 is 176776-68-4.
What is the molecular formula of ICI U24522?
The molecular formula of ICI U24522 is C23H36N4O5.
What is the molecular weight of ICI U24522?
The molecular weight of ICI U24522 is 448.27 g/mol.
Where can I buy ICI U24522?
You can request a quote for ICI U24522 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for ICI U24522?
Yes, KEHONG BIO provides custom synthesis services for ICI U24522 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.