2'-Deoxy-6-thioguanosine 5'-triphosphate
TL;DR: 2'-Deoxy-6-thioguanosine 5'-triphosphate (CAS 17660-38-7) is a chemical compound with molecular formula C10H16N5O12P3S and molecular weight 522.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[[(2R,3S,5R)-5-(2-amino-6-sulfanylidene-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Also Known As: dThioGTP, 6-Thio-dGTP, dG(S)TP, 2'-Deoxy-6-thioguanosine 5'-triphosphate, beta-2'-Deoxy-6-thioguanylate
| Molecular Formula | C10H16N5O12P3S |
|---|---|
| Molecular Weight | 522.97 g/mol |
| LogP | 0.06279 |
| Topological Polar Surface Area | 261.8 Ų |
| Hydrogen Bond Donors | 7 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 8 |
| Exact Mass | 522.9729 |
| Heavy Atoms | 31 |
| Complexity | 1179.4619 |
Chemical Identifiers
| CAS Number | 17660-38-7 |
|---|---|
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2NC(=NC3=S)N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O |
Product Overview
2'-Deoxy-6-thioguanosine 5'-triphosphate (CAS 17660-38-7), with molecular formula C10H16N5O12P3S and molecular weight 522.97 g/mol. IUPAC: [[(2R,3S,5R)-5-(2-amino-6-sulfanylidene-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate.
Chemical Property Profile of 2'-Deoxy-6-thioguanosine 5'-triphosphate
Property Insights of 2'-Deoxy-6-thioguanosine 5'-triphosphate
The XLogP value of 0.06279 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2'-Deoxy-6-thioguanosine 5'-triphosphate. The TPSA of 261.8 Ų indicates high polarity, suggesting 2'-Deoxy-6-thioguanosine 5'-triphosphate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 2'-Deoxy-6-thioguanosine 5'-triphosphate has 7 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-Deoxy-6-thioguanosine 5'-triphosphate?
The CAS number of 2'-Deoxy-6-thioguanosine 5'-triphosphate is 17660-38-7.
What is the molecular formula of 2'-Deoxy-6-thioguanosine 5'-triphosphate?
The molecular formula of 2'-Deoxy-6-thioguanosine 5'-triphosphate is C10H16N5O12P3S.
What is the molecular weight of 2'-Deoxy-6-thioguanosine 5'-triphosphate?
The molecular weight of 2'-Deoxy-6-thioguanosine 5'-triphosphate is 522.97 g/mol.
Where can I buy 2'-Deoxy-6-thioguanosine 5'-triphosphate?
You can request a quote for 2'-Deoxy-6-thioguanosine 5'-triphosphate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-Deoxy-6-thioguanosine 5'-triphosphate?
Yes, KEHONG BIO provides custom synthesis services for 2'-Deoxy-6-thioguanosine 5'-triphosphate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.