Caerulein(4-10), nle(8)- structure

Caerulein(4-10), nle(8)-

TL;DR: Caerulein(4-10), nle(8)- (CAS 17650-98-5) is a chemical compound with molecular formula C45H57N9O14S and molecular weight 979.37 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(3S)-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2R)-2-[[(2S)-2-[[2-[[(2S,3R)-2-[[(2S)-2-amino-3-(4-sulfooxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]-4-oxobutanoic acid

Also Known As: Tymtran, 8-Nle-cer(4-10), Caerulein(4-10), nle(8)-, Nle(8)-ceruletide(4-10), 8-Norleucine-ceruletide(4-10)

CAS: 17650-98-5
Molecular Formula C45H57N9O14S
Molecular Weight 979.37 g/mol
LogP -2.0
Topological Polar Surface Area 389.0 Ų
Hydrogen Bond Donors 12
Hydrogen Bond Acceptors 15
Rotatable Bonds 27
Exact Mass 979.3746
Heavy Atoms 69
Complexity 1870.0

Chemical Identifiers

CAS Number 17650-98-5
SMILES CCCC[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)CNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC4=CC=C(C=C4)OS(=O)(=O)O)N
InChIKey GZCDGEPFXQGWOW-RMNOTBJOSA-N

Patent-Derived Application Labels

Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.

Analytical Reagents (3 patents) Biotechnology (11 patents) Heterocyclic Building Blocks (6 patents) Peptides & Amino Acids (2 patents)

Product Overview

Caerulein(4-10), nle(8)- (CAS 17650-98-5), with molecular formula C45H57N9O14S and molecular weight 979.37 g/mol. IUPAC: (3S)-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2R)-2-[[(2S)-2-[[2-[[(2S,3R)-2-[[(2S)-2-amino-3-(4-sulfooxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]-4-oxobutanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Caerulein(4-10), nle(8)-

XLogP
-2.0
TPSA (Topological Polar Surface Area)
389.0
Hydrogen Bond Donors
12
Hydrogen Bond Acceptors
15
Rotatable Bonds
27
Heavy Atoms
69
Complexity
1870.0
Exact Mass
979.3746
Monoisotopic Mass
979.3746
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Caerulein(4-10), nle(8)-

The XLogP value of -2.0 indicates that Caerulein(4-10), nle(8)- is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 389.0 Ų indicates high polarity, suggesting Caerulein(4-10), nle(8)- may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Caerulein(4-10), nle(8)- has 12 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Caerulein(4-10), nle(8)-?

The CAS number of Caerulein(4-10), nle(8)- is 17650-98-5.

What is the molecular formula of Caerulein(4-10), nle(8)-?

The molecular formula of Caerulein(4-10), nle(8)- is C45H57N9O14S.

What is the molecular weight of Caerulein(4-10), nle(8)-?

The molecular weight of Caerulein(4-10), nle(8)- is 979.37 g/mol.

Where can I buy Caerulein(4-10), nle(8)-?

You can request a quote for Caerulein(4-10), nle(8)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Caerulein(4-10), nle(8)-?

Yes, KEHONG BIO provides custom synthesis services for Caerulein(4-10), nle(8)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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