(6R)-Hydroxy (S,S)-Palonosetron
TL;DR: (6R)-Hydroxy (S,S)-Palonosetron (CAS 176019-33-3) is a chemical compound with molecular formula C19H24N2O2 and molecular weight 312.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3aS,6R)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-6-hydroxy-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one
Also Known As: Palonosetron Impurity 47, (6R)-Hydroxy (S,S)-Palonosetron, (3As,6R)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-6-hydroxy-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one, [3aS-[2(S*),3aalpha,6alpha]]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-Benz[de]isoquinolin-1-one
| Molecular Formula | C19H24N2O2 |
|---|---|
| Molecular Weight | 312.18 g/mol |
| LogP | 2.1474 |
| Topological Polar Surface Area | 43.78 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 312.18378 |
| Heavy Atoms | 23 |
| Complexity | 650.7697 |
Chemical Identifiers
| CAS Number | 176019-33-3 |
|---|---|
| SMILES | C1C[C@H](C2=C3[C@H]1CN(C(=O)C3=CC=C2)[C@@H]4CN5CCC4CC5)O |
Product Overview
(6R)-Hydroxy (S,S)-Palonosetron (CAS 176019-33-3), with molecular formula C19H24N2O2 and molecular weight 312.18 g/mol. IUPAC: (3aS,6R)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-6-hydroxy-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one.
Chemical Property Profile of (6R)-Hydroxy (S,S)-Palonosetron
Property Insights of (6R)-Hydroxy (S,S)-Palonosetron
The XLogP value of 2.1474 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (6R)-Hydroxy (S,S)-Palonosetron. With a topological polar surface area (TPSA) of 43.78 Ų, (6R)-Hydroxy (S,S)-Palonosetron exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (6R)-Hydroxy (S,S)-Palonosetron has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (6R)-Hydroxy (S,S)-Palonosetron?
The CAS number of (6R)-Hydroxy (S,S)-Palonosetron is 176019-33-3.
What is the molecular formula of (6R)-Hydroxy (S,S)-Palonosetron?
The molecular formula of (6R)-Hydroxy (S,S)-Palonosetron is C19H24N2O2.
What is the molecular weight of (6R)-Hydroxy (S,S)-Palonosetron?
The molecular weight of (6R)-Hydroxy (S,S)-Palonosetron is 312.18 g/mol.
Where can I buy (6R)-Hydroxy (S,S)-Palonosetron?
You can request a quote for (6R)-Hydroxy (S,S)-Palonosetron directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (6R)-Hydroxy (S,S)-Palonosetron?
Yes, KEHONG BIO provides custom synthesis services for (6R)-Hydroxy (S,S)-Palonosetron and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.