2-Pyrrolino-dox structure

2-Pyrrolino-dox

TL;DR: 2-Pyrrolino-dox (CAS 175795-76-3) is a chemical compound with molecular formula C31H33NO11 and molecular weight 595.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(7S,9S)-7-[(2R,4S,5S,6S)-4-(2,3-dihydropyrrol-1-yl)-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione

Also Known As: 2-Pyrrolino-dox, 2-Pyrrolinodoxorubicin, 2-pyrollinodoxorubicin, AN 201, AN 204

CAS: 175795-76-3
Molecular Formula C31H33NO11
Molecular Weight 595.21 g/mol
LogP 2.9
Topological Polar Surface Area 183.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 12
Rotatable Bonds 6
Exact Mass 595.2054
Heavy Atoms 43
Complexity 1130.0

Chemical Identifiers

CAS Number 175795-76-3
SMILES C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N6CCC=C6)O
InChIKey NOPNWHSMQOXAEI-PUCKCBAPSA-N

Product Overview

2-Pyrrolino-dox (CAS 175795-76-3), with molecular formula C31H33NO11 and molecular weight 595.21 g/mol. IUPAC: (7S,9S)-7-[(2R,4S,5S,6S)-4-(2,3-dihydropyrrol-1-yl)-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-Pyrrolino-dox

XLogP
2.9
TPSA (Topological Polar Surface Area)
183.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
12
Rotatable Bonds
6
Heavy Atoms
43
Complexity
1130.0
Exact Mass
595.2054
Monoisotopic Mass
595.2054
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-Pyrrolino-dox

The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Pyrrolino-dox. The TPSA of 183.0 Ų indicates high polarity, suggesting 2-Pyrrolino-dox may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 2-Pyrrolino-dox has 5 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-Pyrrolino-dox?

The CAS number of 2-Pyrrolino-dox is 175795-76-3.

What is the molecular formula of 2-Pyrrolino-dox?

The molecular formula of 2-Pyrrolino-dox is C31H33NO11.

What is the molecular weight of 2-Pyrrolino-dox?

The molecular weight of 2-Pyrrolino-dox is 595.21 g/mol.

Where can I buy 2-Pyrrolino-dox?

You can request a quote for 2-Pyrrolino-dox directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-Pyrrolino-dox?

Yes, KEHONG BIO provides custom synthesis services for 2-Pyrrolino-dox and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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