1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine
TL;DR: 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine (CAS 175277-61-9) is a chemical compound with molecular formula C11H12F3N3O2 and molecular weight 275.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-nitro-2-[4-(trifluoromethyl)piperidin-1-yl]pyridine
Also Known As: 1-(5-nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine, 5-Nitro-2-(4-(trifluoromethyl)piperidin-1-yl)pyridine, 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)-piperidine, 5828AD, nitropyridinyltrifluoromethylpiperidine
| Molecular Formula | C11H12F3N3O2 |
|---|---|
| Molecular Weight | 275.09 g/mol |
| LogP | 2.7685 |
| Topological Polar Surface Area | 59.27 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 275.08817 |
| Heavy Atoms | 19 |
| Complexity | 453.24838 |
Chemical Identifiers
| CAS Number | 175277-61-9 |
|---|---|
| SMILES | C1CN(CCC1C(F)(F)F)C2=NC=C(C=C2)[N+](=O)[O-] |
Product Overview
1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine (CAS 175277-61-9), with molecular formula C11H12F3N3O2 and molecular weight 275.09 g/mol. IUPAC: 5-nitro-2-[4-(trifluoromethyl)piperidin-1-yl]pyridine.
Chemical Property Profile of 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine
Property Insights of 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine
The XLogP value of 2.7685 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine. With a topological polar surface area (TPSA) of 59.27 Ų, 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine?
The CAS number of 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine is 175277-61-9.
What is the molecular formula of 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine?
The molecular formula of 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine is C11H12F3N3O2.
What is the molecular weight of 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine?
The molecular weight of 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine is 275.09 g/mol.
Where can I buy 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine?
You can request a quote for 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine?
Yes, KEHONG BIO provides custom synthesis services for 1-(5-Nitro-2-pyridinyl)-4-(trifluoromethyl)piperidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.