2,5-Dichloro-4,6-dimethylnicotinamide structure

2,5-Dichloro-4,6-dimethylnicotinamide

TL;DR: 2,5-Dichloro-4,6-dimethylnicotinamide (CAS 175204-44-1) is a chemical compound with molecular formula C8H8Cl2N2O and molecular weight 218.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2,5-dichloro-4,6-dimethylpyridine-3-carboxamide

Also Known As: 2,5-dichloro-4,6-dimethylnicotinamide, Opicapone Impurity 5, 2,5-dichloro-4,6-dimethylpyridine-3-carboxamide, 3-Pyridinecarboxamide der., 1-Chloro-3-isothiocyanatobenzene

CAS: 175204-44-1
Molecular Formula C8H8Cl2N2O
Molecular Weight 218.00 g/mol
LogP 2.1
Topological Polar Surface Area 56.0 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 218.00137
Heavy Atoms 13
Complexity 212.0

Chemical Identifiers

CAS Number 175204-44-1
SMILES CC1=C(C(=NC(=C1Cl)C)Cl)C(=O)N
InChIKey IHXGELAZSSLGOE-UHFFFAOYSA-N

Product Overview

2,5-Dichloro-4,6-dimethylnicotinamide (CAS 175204-44-1), with molecular formula C8H8Cl2N2O and molecular weight 218.00 g/mol. IUPAC: 2,5-dichloro-4,6-dimethylpyridine-3-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 2,5-Dichloro-4,6-dimethylnicotinamide

XLogP
2.1
TPSA (Topological Polar Surface Area)
56.0
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
13
Complexity
212.0
Exact Mass
218.00137
Monoisotopic Mass
218.00137
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2,5-Dichloro-4,6-dimethylnicotinamide

The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2,5-Dichloro-4,6-dimethylnicotinamide. With a topological polar surface area (TPSA) of 56.0 Ų, 2,5-Dichloro-4,6-dimethylnicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,5-Dichloro-4,6-dimethylnicotinamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2,5-Dichloro-4,6-dimethylnicotinamide?

The CAS number of 2,5-Dichloro-4,6-dimethylnicotinamide is 175204-44-1.

What is the molecular formula of 2,5-Dichloro-4,6-dimethylnicotinamide?

The molecular formula of 2,5-Dichloro-4,6-dimethylnicotinamide is C8H8Cl2N2O.

What is the molecular weight of 2,5-Dichloro-4,6-dimethylnicotinamide?

The molecular weight of 2,5-Dichloro-4,6-dimethylnicotinamide is 218.00 g/mol.

Where can I buy 2,5-Dichloro-4,6-dimethylnicotinamide?

You can request a quote for 2,5-Dichloro-4,6-dimethylnicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2,5-Dichloro-4,6-dimethylnicotinamide?

Yes, KEHONG BIO provides custom synthesis services for 2,5-Dichloro-4,6-dimethylnicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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