4-(5-Bromo-2-thienyl)pyrimidine-2-thiol
TL;DR: 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol (CAS 175202-82-1) is a chemical compound with molecular formula C8H5BrN2S2 and molecular weight 271.91 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(5-bromothiophen-2-yl)-1H-pyrimidine-2-thione
Also Known As: 4-(5-bromothiophen-2-yl)pyrimidine-2-thiol, 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol, 4-(5-bromothien-2-yl)pyrimidine-2-thiol, 4-(5-bromo-2-thienyl)-2-pyrimidinethiol, 6-(5-bromothiophen-2-yl)-1H-pyrimidine-2-thione
| Molecular Formula | C8H5BrN2S2 |
|---|---|
| Molecular Weight | 271.91 g/mol |
| LogP | 3.63019 |
| Topological Polar Surface Area | 28.68 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 271.90775 |
| Heavy Atoms | 13 |
| Complexity | 474.7463 |
Chemical Identifiers
| CAS Number | 175202-82-1 |
|---|---|
| SMILES | C1=C(SC(=C1)Br)C2=CC=NC(=S)N2 |
Product Overview
4-(5-Bromo-2-thienyl)pyrimidine-2-thiol (CAS 175202-82-1), with molecular formula C8H5BrN2S2 and molecular weight 271.91 g/mol. IUPAC: 6-(5-bromothiophen-2-yl)-1H-pyrimidine-2-thione.
Chemical Property Profile of 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol
Property Insights of 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol
The XLogP value of 3.63019 indicates that 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.68 Ų, 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol?
The CAS number of 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol is 175202-82-1.
What is the molecular formula of 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol?
The molecular formula of 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol is C8H5BrN2S2.
What is the molecular weight of 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol?
The molecular weight of 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol is 271.91 g/mol.
Where can I buy 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol?
You can request a quote for 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol?
Yes, KEHONG BIO provides custom synthesis services for 4-(5-Bromo-2-thienyl)pyrimidine-2-thiol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.