4-chloro-6-(trifluoromethyl)-1H-benzimidazole
TL;DR: 4-chloro-6-(trifluoromethyl)-1H-benzimidazole (CAS 175135-13-4) is a chemical compound with molecular formula C8H4ClF3N2 and molecular weight 220.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-6-(trifluoromethyl)-1H-benzimidazole
Also Known As: 4-chloro-6-(trifluoromethyl)-1H-benzimidazole, 4-Chloro-6-(trifluoromethyl)benzimidazole, 4-chloro-6-(trifluoromethyl)-1H-benzo[d]imidazole, buttpark 91\04-10, 4-chloro-6-(trifluoromethyl)-1H-1,3-benzodiazole
| Molecular Formula | C8H4ClF3N2 |
|---|---|
| Molecular Weight | 220.00 g/mol |
| LogP | 3.2351 |
| Topological Polar Surface Area | 28.68 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 220.00151 |
| Heavy Atoms | 14 |
| Complexity | 474.8814 |
Chemical Identifiers
| CAS Number | 175135-13-4 |
|---|---|
| SMILES | C1=C(C=C(C2=C1NC=N2)Cl)C(F)(F)F |
Product Overview
4-chloro-6-(trifluoromethyl)-1H-benzimidazole (CAS 175135-13-4), with molecular formula C8H4ClF3N2 and molecular weight 220.00 g/mol. IUPAC: 4-chloro-6-(trifluoromethyl)-1H-benzimidazole.
Chemical Property Profile of 4-chloro-6-(trifluoromethyl)-1H-benzimidazole
Property Insights of 4-chloro-6-(trifluoromethyl)-1H-benzimidazole
The XLogP value of 3.2351 indicates that 4-chloro-6-(trifluoromethyl)-1H-benzimidazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.68 Ų, 4-chloro-6-(trifluoromethyl)-1H-benzimidazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-chloro-6-(trifluoromethyl)-1H-benzimidazole has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-chloro-6-(trifluoromethyl)-1H-benzimidazole?
The CAS number of 4-chloro-6-(trifluoromethyl)-1H-benzimidazole is 175135-13-4.
What is the molecular formula of 4-chloro-6-(trifluoromethyl)-1H-benzimidazole?
The molecular formula of 4-chloro-6-(trifluoromethyl)-1H-benzimidazole is C8H4ClF3N2.
What is the molecular weight of 4-chloro-6-(trifluoromethyl)-1H-benzimidazole?
The molecular weight of 4-chloro-6-(trifluoromethyl)-1H-benzimidazole is 220.00 g/mol.
Where can I buy 4-chloro-6-(trifluoromethyl)-1H-benzimidazole?
You can request a quote for 4-chloro-6-(trifluoromethyl)-1H-benzimidazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-chloro-6-(trifluoromethyl)-1H-benzimidazole?
Yes, KEHONG BIO provides custom synthesis services for 4-chloro-6-(trifluoromethyl)-1H-benzimidazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.