3-(Trifluoromethyl)dihydrofuran-2(3H)-one
TL;DR: 3-(Trifluoromethyl)dihydrofuran-2(3H)-one (CAS 174744-18-4) is a chemical compound with molecular formula C5H5F3O2 and molecular weight 154.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(trifluoromethyl)oxolan-2-one
Also Known As: 3-(trifluoromethyl)oxolan-2-one, 3-(Trifluoromethyl)dihydrofuran-2(3H)-one, N-betulinyl-glycine, alpha-(Trifluoromethyl)-gamma-butyrolactone, trifluoromethyl butyrolactone
| Molecular Formula | C5H5F3O2 |
|---|---|
| Molecular Weight | 154.02 g/mol |
| LogP | 1.1118 |
| Topological Polar Surface Area | 26.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 154.02417 |
| Heavy Atoms | 10 |
| Complexity | 151.46228 |
Chemical Identifiers
| CAS Number | 174744-18-4 |
|---|---|
| SMILES | C1COC(=O)C1C(F)(F)F |
Product Overview
3-(Trifluoromethyl)dihydrofuran-2(3H)-one (CAS 174744-18-4), with molecular formula C5H5F3O2 and molecular weight 154.02 g/mol. IUPAC: 3-(trifluoromethyl)oxolan-2-one.
Chemical Property Profile of 3-(Trifluoromethyl)dihydrofuran-2(3H)-one
Property Insights of 3-(Trifluoromethyl)dihydrofuran-2(3H)-one
The XLogP value of 1.1118 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-(Trifluoromethyl)dihydrofuran-2(3H)-one. With a topological polar surface area (TPSA) of 26.3 Ų, 3-(Trifluoromethyl)dihydrofuran-2(3H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(Trifluoromethyl)dihydrofuran-2(3H)-one has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(Trifluoromethyl)dihydrofuran-2(3H)-one?
The CAS number of 3-(Trifluoromethyl)dihydrofuran-2(3H)-one is 174744-18-4.
What is the molecular formula of 3-(Trifluoromethyl)dihydrofuran-2(3H)-one?
The molecular formula of 3-(Trifluoromethyl)dihydrofuran-2(3H)-one is C5H5F3O2.
What is the molecular weight of 3-(Trifluoromethyl)dihydrofuran-2(3H)-one?
The molecular weight of 3-(Trifluoromethyl)dihydrofuran-2(3H)-one is 154.02 g/mol.
Where can I buy 3-(Trifluoromethyl)dihydrofuran-2(3H)-one?
You can request a quote for 3-(Trifluoromethyl)dihydrofuran-2(3H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(Trifluoromethyl)dihydrofuran-2(3H)-one?
Yes, KEHONG BIO provides custom synthesis services for 3-(Trifluoromethyl)dihydrofuran-2(3H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.