SRI 8451
TL;DR: SRI 8451 (CAS 174654-92-3) is a chemical compound with molecular formula C16H17N5OS and molecular weight 327.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-[(3-methoxyphenyl)sulfanylmethyl]-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine
Also Known As: SRI 8451, 2,4-Diamino-5-methylpyrido(2,3-d)pyrimidine, 6-((3-methoxyphenylthio)methyl), 0.9 hydrate, 2,4-Diamino-5-methylpyrido[2,3-d]pyrimidine, 6-[(3-methoxyphenylthio)methyl], 0.9 hydrate, 6-(3-Methoxy-phenylsulfanylmethyl)-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine, 6-[(3-methoxyphenyl)sulfanylmethyl]-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine
| Molecular Formula | C16H17N5OS |
|---|---|
| Molecular Weight | 327.12 g/mol |
| LogP | 2.5 |
| Topological Polar Surface Area | 125.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 327.1154 |
| Heavy Atoms | 23 |
| Complexity | 387.0 |
Chemical Identifiers
| CAS Number | 174654-92-3 |
|---|---|
| SMILES | CC1=C2C(=NC(=NC2=NC=C1CSC3=CC=CC(=C3)OC)N)N |
| InChIKey | XEXFECRCBWCTCV-UHFFFAOYSA-N |
Product Overview
SRI 8451 (CAS 174654-92-3), with molecular formula C16H17N5OS and molecular weight 327.12 g/mol. IUPAC: 6-[(3-methoxyphenyl)sulfanylmethyl]-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine.
Chemical Property Profile of SRI 8451
Property Insights of SRI 8451
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for SRI 8451. The TPSA of 125.0 Ų falls within the moderate polarity range, balancing permeability and solubility for SRI 8451. Following Lipinski's Rule of Five, SRI 8451 has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of SRI 8451?
The CAS number of SRI 8451 is 174654-92-3.
What is the molecular formula of SRI 8451?
The molecular formula of SRI 8451 is C16H17N5OS.
What is the molecular weight of SRI 8451?
The molecular weight of SRI 8451 is 327.12 g/mol.
Where can I buy SRI 8451?
You can request a quote for SRI 8451 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for SRI 8451?
Yes, KEHONG BIO provides custom synthesis services for SRI 8451 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.