N-Propionyldemecolcine
TL;DR: N-Propionyldemecolcine (CAS 17445-52-2) is a chemical compound with molecular formula C24H29NO6 and molecular weight 427.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-methyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]propanamide
Also Known As: N-Propionyldemecolcine, Colchicine, N-deacetyl-N-methyl-N-propionyl-, propanamide, n-methyl-n-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-,(s)-, N-Methyl-N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)propanamide, N-Methyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]propanamide
| Molecular Formula | C24H29NO6 |
|---|---|
| Molecular Weight | 427.20 g/mol |
| LogP | 1.8 |
| Topological Polar Surface Area | 74.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 427.1995 |
| Heavy Atoms | 31 |
| Complexity | 785.0 |
Chemical Identifiers
| CAS Number | 17445-52-2 |
|---|---|
| SMILES | CCC(=O)N(C)[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC |
| InChIKey | YZOCEGWMJRCTQH-KRWDZBQOSA-N |
Product Overview
N-Propionyldemecolcine (CAS 17445-52-2), with molecular formula C24H29NO6 and molecular weight 427.20 g/mol. IUPAC: N-methyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]propanamide.
Chemical Property Profile of N-Propionyldemecolcine
Property Insights of N-Propionyldemecolcine
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-Propionyldemecolcine. The TPSA of 74.3 Ų falls within the moderate polarity range, balancing permeability and solubility for N-Propionyldemecolcine. Following Lipinski's Rule of Five, N-Propionyldemecolcine has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-Propionyldemecolcine?
The CAS number of N-Propionyldemecolcine is 17445-52-2.
What is the molecular formula of N-Propionyldemecolcine?
The molecular formula of N-Propionyldemecolcine is C24H29NO6.
What is the molecular weight of N-Propionyldemecolcine?
The molecular weight of N-Propionyldemecolcine is 427.20 g/mol.
Where can I buy N-Propionyldemecolcine?
You can request a quote for N-Propionyldemecolcine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-Propionyldemecolcine?
Yes, KEHONG BIO provides custom synthesis services for N-Propionyldemecolcine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.