Amiloride Hydrochloride
TL;DR: Amiloride Hydrochloride (CAS 17440-83-4) is a chemical compound with molecular formula C6H13Cl2N7O3 and molecular weight 301.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;dihydrate;hydrochloride
Also Known As: Amiloride hydrochloride dihydrate, AMILORIDE HYDROCHLORIDE, Modamide, Midamor, Amiloride HCL
| Molecular Formula | C6H13Cl2N7O3 |
|---|---|
| Molecular Weight | 301.05 g/mol |
| LogP | -2.52 |
| Topological Polar Surface Area | 161.0 Ų |
| Hydrogen Bond Donors | 7 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 1 |
| Exact Mass | 301.0457 |
| Heavy Atoms | 18 |
| Complexity | 279.0 |
| Melting Point | 293.5 °C |
| Solubility | less than 1 mg/mL at 67.1 °F (NTP, 1992) |
Chemical Identifiers
| CAS Number | 17440-83-4 |
|---|---|
| SMILES | C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.O.O.Cl |
| InChIKey | LTKVFMLMEYCWMK-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Amiloride Hydrochloride (CAS 17440-83-4), with molecular formula C6H13Cl2N7O3 and molecular weight 301.05 g/mol. IUPAC: 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;dihydrate;hydrochloride.
Chemical Property Profile of Amiloride Hydrochloride
Property Insights of Amiloride Hydrochloride
The XLogP value of -2.52 indicates that Amiloride Hydrochloride is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 161.0 Ų indicates high polarity, suggesting Amiloride Hydrochloride may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Amiloride Hydrochloride has 7 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Amiloride Hydrochloride?
The CAS number of Amiloride Hydrochloride is 17440-83-4.
What is the molecular formula of Amiloride Hydrochloride?
The molecular formula of Amiloride Hydrochloride is C6H13Cl2N7O3.
What is the molecular weight of Amiloride Hydrochloride?
The molecular weight of Amiloride Hydrochloride is 301.05 g/mol.
Where can I buy Amiloride Hydrochloride?
You can request a quote for Amiloride Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Amiloride Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Amiloride Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.