Makaluvamine K structure

Makaluvamine K

TL;DR: Makaluvamine K (CAS 174232-36-1) is a chemical compound with molecular formula C19H19N3O2 and molecular weight 321.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

10-[2-(4-hydroxyphenyl)ethylamino]-2-methyl-2,7-diazatricyclo[6.3.1.04,12]dodeca-1(12),3,7,9-tetraen-11-one

Also Known As: Makaluvamine K, [2-(4-hydroxyphenyl)ethylamino]-methyl-[?]one, Pyrrolo(4,3,2-de)quinolin-8(1H)-one, 3,4-dihydro-7-((2-(4-hydroxyphenyl)ethyl)amino)-1-methyl-, 1-Methyl-7-[(4-hydroxyphenethyl)amino]-3,4-dihydropyrrolo[4,3,2-de]quinolin-8(1H)-one, 10-(2-(4-hydroxyphenyl)ethylamino)-2-methyl-2,7-diazatricyclo(6.3.1.04,12)dodeca-1(12),3,7,9-tetraen-11-one

CAS: 174232-36-1
Molecular Formula C19H19N3O2
Molecular Weight 321.15 g/mol
LogP 2.3
Topological Polar Surface Area 66.6 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 321.14774
Heavy Atoms 24
Complexity 563.0

Chemical Identifiers

CAS Number 174232-36-1
SMILES CN1C=C2CCN=C3C2=C1C(=O)C(=C3)NCCC4=CC=C(C=C4)O
InChIKey MFJASCFAUMWBMV-UHFFFAOYSA-N

Product Overview

Makaluvamine K (CAS 174232-36-1), with molecular formula C19H19N3O2 and molecular weight 321.15 g/mol. IUPAC: 10-[2-(4-hydroxyphenyl)ethylamino]-2-methyl-2,7-diazatricyclo[6.3.1.04,12]dodeca-1(12),3,7,9-tetraen-11-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Makaluvamine K

XLogP
2.3
TPSA (Topological Polar Surface Area)
66.6
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
24
Complexity
563.0
Exact Mass
321.14774
Monoisotopic Mass
321.14774
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Makaluvamine K

The XLogP value of 2.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Makaluvamine K. The TPSA of 66.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Makaluvamine K. Following Lipinski's Rule of Five, Makaluvamine K has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Makaluvamine K?

The CAS number of Makaluvamine K is 174232-36-1.

What is the molecular formula of Makaluvamine K?

The molecular formula of Makaluvamine K is C19H19N3O2.

What is the molecular weight of Makaluvamine K?

The molecular weight of Makaluvamine K is 321.15 g/mol.

Where can I buy Makaluvamine K?

You can request a quote for Makaluvamine K directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Makaluvamine K?

Yes, KEHONG BIO provides custom synthesis services for Makaluvamine K and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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