Bryostatin 18
TL;DR: Bryostatin 18 (CAS 173107-74-9) is a chemical compound with molecular formula C42H64O15 and molecular weight 808.42 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(5Z,8E,13Z)-1,11,21-trihydroxy-17-(1-hydroxyethyl)-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-25-yl] 2,2-dimethylpropanoate
Also Known As: Bryostatin 18, [(5Z,8E,13Z)-1,11,21-Trihydroxy-17-(1-hydroxyethyl)-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-25-yl] 2,2-dimethylpropanoate, Propanoic acid, 2,2-dimethyl-, (1S,3S,5Z,7R,8E,11R,13Z,15S,17R,21R,23R,25S)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-25-yl, Propanoic acid, 2,2-dimethyl-, 1,11,21-trihydroxy-17-(1-hydroxyethyl)-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29- tetraoxatetracyclo(21.3.1.13,7.111,15)nonacos-8-en-25-yl ester, (1S-(1R*,3R*,5Z,7S*,8E,11S*,13Z,15R*,17S*(S*),21S*,23S*,25R*))-
| Molecular Formula | C42H64O15 |
|---|---|
| Molecular Weight | 808.42 g/mol |
| LogP | 3.8719 |
| Topological Polar Surface Area | 213.81 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 15 |
| Rotatable Bonds | 4 |
| Exact Mass | 808.4245 |
| Heavy Atoms | 57 |
| Complexity | 1570.3469 |
Chemical Identifiers
| CAS Number | 173107-74-9 |
|---|---|
| SMILES | CC(C1CC2C/C(=C/C(=O)OC)/CC(O2)(C(/C=C/C3C/C(=C\C(=O)OC)/CC(O3)CC4(C(C(CC(O4)CC(CC(=O)O1)O)OC(=O)C(C)(C)C)(C)C)O)(C)C)O)O |
Product Overview
Bryostatin 18 (CAS 173107-74-9), with molecular formula C42H64O15 and molecular weight 808.42 g/mol. IUPAC: [(5Z,8E,13Z)-1,11,21-trihydroxy-17-(1-hydroxyethyl)-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-25-yl] 2,2-dimethylpropanoate.
Chemical Property Profile of Bryostatin 18
Property Insights of Bryostatin 18
The XLogP value of 3.8719 indicates that Bryostatin 18 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 213.81 Ų indicates high polarity, suggesting Bryostatin 18 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Bryostatin 18 has 4 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Bryostatin 18?
The CAS number of Bryostatin 18 is 173107-74-9.
What is the molecular formula of Bryostatin 18?
The molecular formula of Bryostatin 18 is C42H64O15.
What is the molecular weight of Bryostatin 18?
The molecular weight of Bryostatin 18 is 808.42 g/mol.
Where can I buy Bryostatin 18?
You can request a quote for Bryostatin 18 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Bryostatin 18?
Yes, KEHONG BIO provides custom synthesis services for Bryostatin 18 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.