(-)-FR-181877
TL;DR: (-)-FR-181877 (CAS 172936-99-1) is a chemical compound with molecular formula C30H28N2O4 and molecular weight 480.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[(6S)-6-[(3-benzhydryl-6-oxopyridazin-1-yl)methyl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acid
Also Known As: (-)-FR-181877, Acetic acid, (((6S)-6-((3-(diphenylmethyl)-6-oxo-1(6H)-pyridazinyl)methyl)-5,6,7,8-tetrahydro-1-naphthalenyl)oxy)-, J1.446.379H, 2-[[(6S)-6-[(3-benzhydryl-6-oxopyridazin-1-yl)methyl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acid, Acetic acid, ((6-((3-(diphenylmethyl)-6-oxo-1(6H)-pyridazinyl)methyl)-5,6,7,8-tetrahydro-1-naphthalenyl)oxy)-, (S)-
| Molecular Formula | C30H28N2O4 |
|---|---|
| Molecular Weight | 480.20 g/mol |
| LogP | 4.692 |
| Topological Polar Surface Area | 81.42 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 8 |
| Exact Mass | 480.2049 |
| Heavy Atoms | 36 |
| Complexity | 1360.1401 |
Chemical Identifiers
| CAS Number | 172936-99-1 |
|---|---|
| SMILES | C1CC2=C(C[C@H]1CN3C(=O)C=CC(=N3)C(C4=CC=CC=C4)C5=CC=CC=C5)C=CC=C2OCC(=O)O |
Product Overview
(-)-FR-181877 (CAS 172936-99-1), with molecular formula C30H28N2O4 and molecular weight 480.20 g/mol. IUPAC: 2-[[(6S)-6-[(3-benzhydryl-6-oxopyridazin-1-yl)methyl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acid.
Chemical Property Profile of (-)-FR-181877
Property Insights of (-)-FR-181877
The XLogP value of 4.692 indicates that (-)-FR-181877 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.42 Ų falls within the moderate polarity range, balancing permeability and solubility for (-)-FR-181877. Following Lipinski's Rule of Five, (-)-FR-181877 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (-)-FR-181877?
The CAS number of (-)-FR-181877 is 172936-99-1.
What is the molecular formula of (-)-FR-181877?
The molecular formula of (-)-FR-181877 is C30H28N2O4.
What is the molecular weight of (-)-FR-181877?
The molecular weight of (-)-FR-181877 is 480.20 g/mol.
Where can I buy (-)-FR-181877?
You can request a quote for (-)-FR-181877 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (-)-FR-181877?
Yes, KEHONG BIO provides custom synthesis services for (-)-FR-181877 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.