20alpha-Hydroxycortisol
TL;DR: 20alpha-Hydroxycortisol (CAS 17287-49-9) is a chemical compound with molecular formula C21H32O5 and molecular weight 364.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8S,9S,10R,11S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Also Known As: 20alpha-Dihydrocortisol, 20-alpha-Dihydrocortisol, 20-Hydroxycortisol, 20alpha-hydroxycortisol, 20beta-Dihydrocortisol
| Molecular Formula | C21H32O5 |
|---|---|
| Molecular Weight | 364.22 g/mol |
| LogP | 0.8 |
| Topological Polar Surface Area | 98.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 364.22498 |
| Heavy Atoms | 26 |
| Complexity | 644.0 |
Chemical Identifiers
| CAS Number | 17287-49-9 |
|---|---|
| SMILES | C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4([C@H](CO)O)O)C)O |
| InChIKey | AWWCEQOCFFQUKS-FJWDNACWSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
20alpha-Hydroxycortisol (CAS 17287-49-9), with molecular formula C21H32O5 and molecular weight 364.22 g/mol. IUPAC: (8S,9S,10R,11S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 20alpha-Hydroxycortisol
Property Insights of 20alpha-Hydroxycortisol
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 20alpha-Hydroxycortisol. The TPSA of 98.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 20alpha-Hydroxycortisol. Following Lipinski's Rule of Five, 20alpha-Hydroxycortisol has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 20alpha-Hydroxycortisol?
The CAS number of 20alpha-Hydroxycortisol is 17287-49-9.
What is the molecular formula of 20alpha-Hydroxycortisol?
The molecular formula of 20alpha-Hydroxycortisol is C21H32O5.
What is the molecular weight of 20alpha-Hydroxycortisol?
The molecular weight of 20alpha-Hydroxycortisol is 364.22 g/mol.
Where can I buy 20alpha-Hydroxycortisol?
You can request a quote for 20alpha-Hydroxycortisol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 20alpha-Hydroxycortisol?
Yes, KEHONG BIO provides custom synthesis services for 20alpha-Hydroxycortisol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.