N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2
TL;DR: N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2 (CAS 172617-89-9) is a chemical compound with molecular formula C47H65N15O9 and molecular weight 983.51 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-[[(2S)-2-acetamidohexanoyl]amino]-N-[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]pentanediamide
Also Known As: N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2, (2S)-2-[[(2S)-2-Acetamidohexanoyl]amino]-N-[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]pentanediamide, Acetyl-(Nle4,Gln5,D-Phe7,D-Trp9)-a-MSH (4-10) amide, Glycinamide, N-acetyl-L-norleucyl-L-glutaminyl-L-histidyl-D-phenylalanyl-L-arginyl-D-tryptophyl-, Acetyl-(Nle4,Gln5,D-Phe7,D-Trp9)-alpha-MSH (4-10) amide
| Molecular Formula | C47H65N15O9 |
|---|---|
| Molecular Weight | 983.51 g/mol |
| LogP | -2.0416 |
| Topological Polar Surface Area | 398.75 Ų |
| Hydrogen Bond Donors | 13 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 30 |
| Exact Mass | 983.509 |
| Heavy Atoms | 71 |
| Complexity | 2474.3665 |
Chemical Identifiers
| CAS Number | 172617-89-9 |
|---|---|
| SMILES | CCCC[C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)N)NC(=O)C |
Product Overview
N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2 (CAS 172617-89-9), with molecular formula C47H65N15O9 and molecular weight 983.51 g/mol. IUPAC: (2S)-2-[[(2S)-2-acetamidohexanoyl]amino]-N-[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]pentanediamide.
Chemical Property Profile of N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2
Property Insights of N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2
The XLogP value of -2.0416 indicates that N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 398.75 Ų indicates high polarity, suggesting N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2 has 13 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2?
The CAS number of N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2 is 172617-89-9.
What is the molecular formula of N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2?
The molecular formula of N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2 is C47H65N15O9.
What is the molecular weight of N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2?
The molecular weight of N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2 is 983.51 g/mol.
Where can I buy N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2?
You can request a quote for N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2?
Yes, KEHONG BIO provides custom synthesis services for N-Acetyl-nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.