KW-8232 free base
TL;DR: KW-8232 free base (CAS 170365-25-0) is a chemical compound with molecular formula C36H37ClN4O3 and molecular weight 608.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[3-[bis(4-hydroxyphenyl)methyl]-1-[2-(dimethylamino)ethyl]indol-2-yl]-[4-(2-chlorophenyl)piperazin-1-yl]methanone
Also Known As: KW-8232 free base, Kw 8232, J1.013.129D, [3-[bis(4-hydroxyphenyl)methyl]-1-[2-(dimethylamino)ethyl]indol-2-yl]-[4-(2-chlorophenyl)piperazin-1-yl]methanone, Methanone, (3-(bis(4-hydroxyphenyl)methyl)-1-(2-(dimethylamino)ethyl)-1H-indol-2-yl)(4-(2-chlorophenyl)-1-piperazinyl)-
| Molecular Formula | C36H37ClN4O3 |
|---|---|
| Molecular Weight | 608.26 g/mol |
| LogP | 6.4101 |
| Topological Polar Surface Area | 72.18 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 8 |
| Exact Mass | 608.25543 |
| Heavy Atoms | 44 |
| Complexity | 1711.8 |
Chemical Identifiers
| CAS Number | 170365-25-0 |
|---|---|
| SMILES | CN(C)CCN1C2=CC=CC=C2C(=C1C(=O)N3CCN(CC3)C4=CC=CC=C4Cl)C(C5=CC=C(C=C5)O)C6=CC=C(C=C6)O |
Product Overview
KW-8232 free base (CAS 170365-25-0), with molecular formula C36H37ClN4O3 and molecular weight 608.26 g/mol. IUPAC: [3-[bis(4-hydroxyphenyl)methyl]-1-[2-(dimethylamino)ethyl]indol-2-yl]-[4-(2-chlorophenyl)piperazin-1-yl]methanone.
Chemical Property Profile of KW-8232 free base
Property Insights of KW-8232 free base
The XLogP value of 6.4101 indicates that KW-8232 free base is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.18 Ų falls within the moderate polarity range, balancing permeability and solubility for KW-8232 free base. Following Lipinski's Rule of Five, KW-8232 free base has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of KW-8232 free base?
The CAS number of KW-8232 free base is 170365-25-0.
What is the molecular formula of KW-8232 free base?
The molecular formula of KW-8232 free base is C36H37ClN4O3.
What is the molecular weight of KW-8232 free base?
The molecular weight of KW-8232 free base is 608.26 g/mol.
Where can I buy KW-8232 free base?
You can request a quote for KW-8232 free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for KW-8232 free base?
Yes, KEHONG BIO provides custom synthesis services for KW-8232 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.