(S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine
TL;DR: (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine (CAS 169675-08-5) is a chemical compound with molecular formula C11H12ClFN2 and molecular weight 226.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-1-(6-chloro-5-fluoroindol-1-yl)propan-2-amine
Also Known As: Ro60-0175, Ro60-0175 free base, GTPL166, Ro 60-0175, Ro-60-0175
| Molecular Formula | C11H12ClFN2 |
|---|---|
| Molecular Weight | 226.07 g/mol |
| LogP | 2.781 |
| Topological Polar Surface Area | 30.95 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 226.0673 |
| Heavy Atoms | 15 |
| Complexity | 490.53873 |
Chemical Identifiers
| CAS Number | 169675-08-5 |
|---|---|
| SMILES | C[C@@H](CN1C=CC2=CC(=C(C=C21)Cl)F)N |
Product Overview
(S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine (CAS 169675-08-5), with molecular formula C11H12ClFN2 and molecular weight 226.07 g/mol. IUPAC: (2S)-1-(6-chloro-5-fluoroindol-1-yl)propan-2-amine.
Chemical Property Profile of (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine
Property Insights of (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine
The XLogP value of 2.781 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine. With a topological polar surface area (TPSA) of 30.95 Ų, (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine?
The CAS number of (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine is 169675-08-5.
What is the molecular formula of (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine?
The molecular formula of (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine is C11H12ClFN2.
What is the molecular weight of (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine?
The molecular weight of (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine is 226.07 g/mol.
Where can I buy (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine?
You can request a quote for (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine?
Yes, KEHONG BIO provides custom synthesis services for (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.