Desmethylmedazepam structure

Desmethylmedazepam

TL;DR: Desmethylmedazepam (CAS 1694-78-6) is a chemical compound with molecular formula C15H13ClN2 and molecular weight 256.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

7-chloro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine

Also Known As: Desmethylmedazepam, Normedazepam, N-Desmethylmedazepam, N-Desmethyl-medazepam, Ro 5-2925

CAS: 1694-78-6
Molecular Formula C15H13ClN2
Molecular Weight 256.08 g/mol
LogP 4.3
Topological Polar Surface Area 24.4 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 256.07672
Heavy Atoms 18
Complexity 310.0

Chemical Identifiers

CAS Number 1694-78-6
SMILES C1CN=C(C2=C(N1)C=CC(=C2)Cl)C3=CC=CC=C3
InChIKey JZWOKDTXYPEJEW-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (5 patents) Organic Building Blocks (1 patents) Pharmaceutical Intermediates (2 patents)

Product Overview

Desmethylmedazepam (CAS 1694-78-6), with molecular formula C15H13ClN2 and molecular weight 256.08 g/mol. IUPAC: 7-chloro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Desmethylmedazepam

XLogP
4.3
TPSA (Topological Polar Surface Area)
24.4
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
18
Complexity
310.0
Exact Mass
256.07672
Monoisotopic Mass
256.07672
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Desmethylmedazepam

The XLogP value of 4.3 indicates that Desmethylmedazepam is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 24.4 Ų, Desmethylmedazepam exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Desmethylmedazepam has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Desmethylmedazepam?

The CAS number of Desmethylmedazepam is 1694-78-6.

What is the molecular formula of Desmethylmedazepam?

The molecular formula of Desmethylmedazepam is C15H13ClN2.

What is the molecular weight of Desmethylmedazepam?

The molecular weight of Desmethylmedazepam is 256.08 g/mol.

Where can I buy Desmethylmedazepam?

You can request a quote for Desmethylmedazepam directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Desmethylmedazepam?

Yes, KEHONG BIO provides custom synthesis services for Desmethylmedazepam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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