Cryptophycin 8
TL;DR: Cryptophycin 8 (CAS 168482-36-8) is a chemical compound with molecular formula C35H44Cl2N2O8 and molecular weight 690.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3S,6R,10R,13E,16S)-16-[(2R,3R,4S)-4-chloro-3-hydroxy-4-phenylbutan-2-yl]-10-[(3-chloro-4-methoxyphenyl)methyl]-6-methyl-3-(2-methylpropyl)-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone
Also Known As: Cryptophycin 8, (3S,6R,10R,13E,16S)-16-((2R,3R,4S)-4-chloro-3-hydroxy-4-phenylbutan-2-yl)-10-((3-chloro-4-methoxyphenyl)methyl)-6-methyl-3-(2-methylpropyl)-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone, (3S,6R,10R,13E,16S)-16-[(2R,3R,4S)-4-chloro-3-hydroxy-4-phenylbutan-2-yl]-10-[(3-chloro-4-methoxyphenyl)methyl]-6-methyl-3-(2-methylpropyl)-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone, RefChem:128636
| Molecular Formula | C35H44Cl2N2O8 |
|---|---|
| Molecular Weight | 690.25 g/mol |
| LogP | 4.9349 |
| Topological Polar Surface Area | 140.26 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 9 |
| Exact Mass | 690.2475 |
| Heavy Atoms | 47 |
| Complexity | 1403.2029 |
Chemical Identifiers
| CAS Number | 168482-36-8 |
|---|---|
| SMILES | C[C@@H]1CNC(=O)[C@H](NC(=O)/C=C/C[C@H](OC(=O)[C@@H](OC1=O)CC(C)C)[C@H](C)[C@H]([C@H](C2=CC=CC=C2)Cl)O)CC3=CC(=C(C=C3)OC)Cl |
Product Overview
Cryptophycin 8 (CAS 168482-36-8), with molecular formula C35H44Cl2N2O8 and molecular weight 690.25 g/mol. IUPAC: (3S,6R,10R,13E,16S)-16-[(2R,3R,4S)-4-chloro-3-hydroxy-4-phenylbutan-2-yl]-10-[(3-chloro-4-methoxyphenyl)methyl]-6-methyl-3-(2-methylpropyl)-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone.
Chemical Property Profile of Cryptophycin 8
Property Insights of Cryptophycin 8
The XLogP value of 4.9349 indicates that Cryptophycin 8 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 140.26 Ų indicates high polarity, suggesting Cryptophycin 8 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Cryptophycin 8 has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Cryptophycin 8?
The CAS number of Cryptophycin 8 is 168482-36-8.
What is the molecular formula of Cryptophycin 8?
The molecular formula of Cryptophycin 8 is C35H44Cl2N2O8.
What is the molecular weight of Cryptophycin 8?
The molecular weight of Cryptophycin 8 is 690.25 g/mol.
Where can I buy Cryptophycin 8?
You can request a quote for Cryptophycin 8 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Cryptophycin 8?
Yes, KEHONG BIO provides custom synthesis services for Cryptophycin 8 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.